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Study Group > Pharma Dr, Mariko lec 12 > Flashcards

Pharma Dr, Mariko lec 12 Flashcards

1
Q

benzodiazepines
mechanism
application

A
  • allosterically enhance the action of GABA on GABA A receptors
  • anti-convilsants, sedatives
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2
Q

General anesthetics

mechanism

A

modification of membrane protein activity including GABA A receptor

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3
Q

GABA A receptor
function
localization

A
  • inhibitory synaptic transmission
  • clamp the membrane potential negative and decrease the electrical excitability

-entire brain

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4
Q

GABA A receptor
classification
properties

A

ligand gated Cl-channels

Cl- permeable

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5
Q

GABA A receptor associated drugs

names 2

A

general anesthetics

benzodiazepines

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