Pharm Of Skin (continued) Flashcards
Indication for Tretinoin for skin conditions?
acne vulgaris
Decreases cohesion between epidermal cells and increases epidermal cell turnover
Expulsion of open comedones and transforms closed into open ones
ADR of Tretinoin?
teratogenic potential; increased by exposure to sunlight
Adapalene has what advantage over retinoid acid use?
Photochemically stable and less irritating
Indications Isotretinoin?
Severe cystic acne not responding to other topical treatment
Contraindications of Isotretinoin?
pregnant women and women willing to be pregnant
ADR of Isotretinoin?
hypervitaminosis A
Contraindications of isotretinoin?
pseudotumor cerebri, teratogenic
Name a topical corictosteroid used in treatment of psoriasis?
Triamcinolone
MOA topical corticosteroids when treating psoriasis?
Inhibit epidermal cell mitosis effective for psoriasis
Immunosuppressant
Anti inflammatory
ADR topical steroids?
hypopigmentation
allergic contact dermatitis
cig paper skin
steroid acne
Indications calcipotriene and Calcitriol?
plaque type psoriasis vulgaris
Tazarotene indications?
plaque psoriasis
MOA Tazarotene?
anti-inflammatory and anti-proliferative
Indications for Acitretin?
pustular forms of psoriasis
Tar MOA in treatment of psoriasis?
Inhibit excessive skin proliferation and anti inflammatory action.