Dermatopathology 03

Question 1

Difference between a vesicle, bulla and blister.

Answer 1

Vesicle: Fluid-filled raised lesion < 5 mm across
Bulla: Fluid-filled raised lesion > 5 mm across
Blister is a common term for either

Question 2

Name the layer of skin affected and the condition.

Answer 2

Label accordingly

Question 3

Label the type of Pemphigus seen in A and B.

Answer 3

A. P. vulgaris
B. P. foliaceous

Question 4

Describe the appearance of the lesions in those with Pemphigus vegetans.

Answer 4

Rare, large, moist, verrucous (wartlike), vegetating plaques studded with pustules on the groin,
axillae, and flexural surfaces

Question 5

Describe the layer of skin implicated in pemphigus foliaceus.

Answer 5

blisters in the superficial epidermis at the level of S. granulosum

Question 6

Epidemiology of P. foliaceus.

Answer 6

endemic in Brazil (Fogo selvagem)

Question 7

Describe what P. erythematosus is and what area of the body is typically involved.

Answer 7

Localized, less severe form of pemphigus foliaceus that may selectively involve the malar area of the face in a lupus erythematosus-like fashion

Question 8

Paraneoplastic pemphigus is most commonly associated with what condition?

Answer 8

non-Hodgkin lymphoma

Question 9

What condition is being seen here?

Answer 9

P. foliaceus

Question 10

What is the function of the hemidesmosomes?

Answer 10

to link basal keratinocytes to the underlying basement membrane

Question 11

What is the condition being seen here?

Answer 11

Bullous pemphigoid

Question 12

What is the condition being seen here?

Answer 12

bullous pemphigoid.