Pharm- Antithrombic/ anticoagulant

Question 1

Warfarin- Mech of action

Answer 1

Interferes with coagulation factor- Vitamin K

Question 2

Warfarin- Clinical use

Answer 2

Anticoagulant- DVT, thromboembolism,

Question 3

Warfarin- side effects

Answer 3

hemorrhage, teratogenic, vit. K deficienct

Question 4

Heparin- Mech of action

Answer 4

Prevents fibrin formation- anticoagulant

Question 5

Heparin- Clinical use

Answer 5

Acute DVT, pulmonary embolism

Question 6

Heparin- Side effects

Answer 6

hemorrhage, hypersensativity, thrombosis

Question 7

Dabigatran- mech of action

Answer 7

Anticoagulant.Thrombin inhibition

Question 8

Dabigatran- Clinical use

Answer 8

Prevent stroke, emebolism

Question 9

Dabigatran- Side effects

Answer 9

Hemorrhage, GI

Question 10

Low molecular weight heparin

Answer 10

Anticoagulant- accelerates antithrombin

Question 11

LMWH- Clinical use

Answer 11

DVT, pulm emb. Can be injected

Question 12

Clopidogrel (plavix)- mech of action

Answer 12

antiplateletInhibits binding of platelets to fibrinogen & each other

Question 13

Aspirin- Mech of action

Answer 13

Antiplatelet- COX inhibitor- cumulative effect

Question 14

Clopidogrel- clinical uses

Answer 14

prevention of atherosclerotic events following MI or stroke

Question 15

Clopidogrel- Adverse effects

Answer 15

Bleeding, hemorrhage, pruities

Question 16

Aspirin- clinical uses

Answer 16

Prevention of ischemia- cerebral and myocardial

Question 17

Aspirin- adverse effects

Answer 17

internal bleening, stomach ulcers

Question 18

Ticlopidine

Answer 18

Same as clopidogrel

Question 19

Dipyridamole

Answer 19

COX inhibitor, used in conjunction with aspirin & warfarin.