pharm Flashcards

1
Q

Acetaminophen

A

N-acetylcysteine

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2
Q

Salicylates

A

NaHCO3

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3
Q

Amphetamines

A

NH4Cl

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4
Q

Acetylcholinesterase inhibitors, organophoshates

A

Atropine, pralidoxime

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5
Q

Antimuscarinic, anticholinergic agents

A

physostigmine salicylate, control hyperthermia

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6
Q

B-blockers

A

Glucagon

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7
Q

Digitalis

A

Stabilize K+, lidocaine, anti-dig Fab, Mg2+

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8
Q

Iron

A

Deferoxamine, deferasirox

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9
Q

Lead

A

CaEDTA, dimercaprol, succimer, penicillamine

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10
Q

Mercury, arsenic, gold

A

Dimercaprol, succimer

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11
Q

Copper, arsenic, gold

A

penicillamine

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12
Q

Cyanide

A

Nitrite + thiosulfate, hydroxycobalmin

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13
Q

Methemoglobin

A

Methylene Blue, Vitamin C

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14
Q

Carbon Monoxide

A

100% O2, hyperbaric O2

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15
Q

Methanol, ethylene glycol

A

Fomepizole, dialysis

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16
Q

Opioids

A

Naloxone/naltrexone

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17
Q

Benzodiazepines

A

Flumazenil

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18
Q

TCAs

A

NaHCO3

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19
Q

Heparine

A

Protamine

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20
Q

Warfarin

A

Vitamin K, fresh frozen plasma

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21
Q

tPA, sterptokinase, urokinase

A

Aminocaproic acid

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22
Q

Theophylline

A

B-blocker

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23
Q

Coronary vasospasm

A

Cocaine, sumatriptan, ergot alkaloids

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24
Q

Cutaneous flushing

A

Vancomycin, adenosine, niacin, CCB

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25
Dilated cardiomyopathy
Doxorubicin, daunorubicin
26
Torsades de pointes
Class III (sotalol) and class Ia
27
Agranulocytosis
Clozapine, Carbamazepine, Colchicine, Propylthiouracil, Methimazole, Dapsone
28
Aplastic anemia
Chloramphenicol, benzene, NSAIDS, propylthiouracil, methimazole
29
Direct Coombs positive hemolytic anemia
Methyldopa, penicillin
30
Gray Baby Syndrome
Chloramphenicol
31
Hemolysis in G6PD deficient patients
Isoniazid, Sulfonamides, Primaquine, Aspirin, Ibuprofen, Nitrofurantoin
32
Megaloblastic anemia
Phenytoin, Methotrexate, Sulfa drugs
33
Thrombotic complications
OCPS
34
Cough
Ace inhibitors
35
Pulmonary fibrosis
Bleomycin, amiodarone, busulfan
36
Acute cholestatic hepatitis, jaundice
Erythromycin
37
Focal to massive hepatic necrosis
Halothane, Amanita phalloides, Valproic acid, Acetaminophen
38
Hepatitis
INH
39
Pseudomembranous colitis
Clindamycin, ampicillin
40
Adrenocortical insufficiency
Glucocorticoid withdrawl
41
Gynecomastia
Spironolactone, Digitalis, Cimetidine, chronic alcohol use, estrogens, Ketoconazole
42
Hot flashes
Tamoxifen, clomphine
43
Hyperglycemia
Niacin, tacrolimus, protease inhibitors, HCTZ, corticosteroids
44
Hypothyroidism
Lithium, amiodarone, sulfonamides
45
Fat redistribution
Glucocorticoids, protease inhibitors
46
Gingival Hyperplasia
Phenytoin, verapamil
47
Gout
Furosemide, thiazides, niacin, cyclosporin
48
Myopathies
Fibrates, Niacin, Colchicine, Hydroxychloroquine, Interferon-a, Penicillamine, statins, glucocorticoids
49
osteoporosis
corticosteroids, heparin
50
Photosensitivity
Sulfonamides, amiodarone, tetracycline
51
Rash(steven johnson syndrome)
Penicillin, ethosuximide, carbamazepine, sulfa drugs, lamotrigine, allopurinol, phenytoin, phenobarbital
52
SLE like syndrome
Hydralazine, INH, Procainamide, Phenytoin
53
Teeth(kids)
tetracycline
54
Tendonitis, tendon rupture, cartilage damage
Fluroquinolones
55
Diabetes insipidus
Lithium, demeclocycline
56
Fanconis syndrome
Expired tetracycline
57
Hemorrhagic cystitis
Cyclophosphamide, ifosfamide.
58
Interstitial Nephritis
Methicillin, NSAIDs, Furosemide
59
SIADH
Carbamzepine, cyclophosphamide
60
Cinchonism
Quinidine
61
Parkinson like syndrome
Antipsychotics, reserpine, metoclopramide
62
Seizures
Isoniazid, Bupropion, Imipenem, tramadol, enflurane, metoclopramide
63
Tardive dyskinesia
antipsychotics
64
Antimuscarinic
atropine, TCAs, H1-blockers, neuroleptics
65
Disulfiram-like reaction
Metronidazole, certain cephalosporins, procarbazine, 1st gen sulfonylureas
66
Nephrotoxicity/ototoxicity
Aminoglycosides, vancomycin, loop diuretics, cisplatin
67
P450 inducers
Momma Barb Steals Phen and Refuses Greasy Carbs Chronically ``` Modafinil Barbiturates St Johns wort Pheyntoin Rifampin Griseofulvin Carbamazepine Chronic alcohol use ```
68
P450 inhibitors
MAGIC RACKS in GQ ``` Macrolides Amiodarone Grape juice Isoniazid Cimetidine Ritonavir Acute alcohol abuse Ciprofloxacin Ketoconazole Sulfonamides Gemfibrozil Quinidine ```