Tumors Misc Flashcards
Tumor marker: PSA
prostate-specific antigen. Elevated in BPH and prostatitis. Questionable risk/benefit for screening
Tumor marker: Bombesin
Neuroblastoma, lung and gastric cancer
Tumor marker: prostatic acid phosphatase
prostate carcinoma
Tumor marker: CEA
CarcinoEmbryonic Antigen. Nonspecific but produced in 70% of colorectal and pancreatic cancers.
Tumor marker: a-fetoprotein
normally made in fetus. Hepatocellular carcinoma. Nonseminomatous germ cell tumors
Tumor marker: B-hCG
Hydatiform moles and choriocarcinomas, Associated with pregancy
Tumor marker: CA-125
ovarian cancer
Tumor marker: S-100
melanoma, neural tumors, schwannomas
Tumor marker: alkaline phosphatase
metastase to bone, liver, pagets disease of bone.
Tumor marker: trap
Hairy Cell leukemia (B cell)
Tumor marker: CA-19-9
Pancreatic adenocarcinoma
Tumor marker: Calcitonin
Medullary thyroid carcinoma
HTLV-1
Adult T-cell leukemia/lymphoma
HBV,HCV
Hepatocellular carcinoma
EBV
Burkitt’s lymphoma, Hodgkins lymphoma, nasopharyngeal carcinoma
HPV
Cervical carcinoma, penile/anal carcinoma, upper respiratory SCC
HHV-8
Kaposi’s sarcoma
H.Pylori
Gastric adenocarcinoma and Maltoma
Schistosoma haematobium
Bladder cancer (squamous cell)
Liver fluke (clonorchis sinensis)
Cholangiocarcinoma
Aflatoxin
hepatocellular carcinoma
Vinyl chloride
Liver, angiosarcoma
Carbon tetrachloride
liver, central lobular necrosis, fatty change
Nitrosamines (smoked foods)
Gastric cancer
Cigarette smoke
Larynx squamous cell carcinoma, lung squamous cell and small cell, renal cell carcinoma, bladder transitional cell carcinoma, pancreatic adenocarcinoma
Asbests
Mesothelioma and Bronchogenic carcinoma
Arsenic
squamous cell carcinoma of skin and liver angiosarcoma
Naphthalene
bladder transitional cell carcinoma
alkylating agents
leukemia