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Path > Tumors Misc > Flashcards

Tumors Misc Flashcards

1
Q

Tumor marker: PSA

A

prostate-specific antigen. Elevated in BPH and prostatitis. Questionable risk/benefit for screening

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2
Q

Tumor marker: Bombesin

A

Neuroblastoma, lung and gastric cancer

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3
Q

Tumor marker: prostatic acid phosphatase

A

prostate carcinoma

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4
Q

Tumor marker: CEA

A

CarcinoEmbryonic Antigen. Nonspecific but produced in 70% of colorectal and pancreatic cancers.

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5
Q

Tumor marker: a-fetoprotein

A

normally made in fetus. Hepatocellular carcinoma. Nonseminomatous germ cell tumors

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6
Q

Tumor marker: B-hCG

A

Hydatiform moles and choriocarcinomas, Associated with pregancy

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7
Q

Tumor marker: CA-125

A

ovarian cancer

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8
Q

Tumor marker: S-100

A

melanoma, neural tumors, schwannomas

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9
Q

Tumor marker: alkaline phosphatase

A

metastase to bone, liver, pagets disease of bone.

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10
Q

Tumor marker: trap

A

Hairy Cell leukemia (B cell)

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11
Q

Tumor marker: CA-19-9

A

Pancreatic adenocarcinoma

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12
Q

Tumor marker: Calcitonin

A

Medullary thyroid carcinoma

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13
Q

HTLV-1

A

Adult T-cell leukemia/lymphoma

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14
Q

HBV,HCV

A

Hepatocellular carcinoma

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15
Q

EBV

A

Burkitt’s lymphoma, Hodgkins lymphoma, nasopharyngeal carcinoma

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16
Q

HPV

A

Cervical carcinoma, penile/anal carcinoma, upper respiratory SCC

17
Q

HHV-8

A

Kaposi’s sarcoma

18
Q

H.Pylori

A

Gastric adenocarcinoma and Maltoma

19
Q

Schistosoma haematobium

A

Bladder cancer (squamous cell)

20
Q

Liver fluke (clonorchis sinensis)

A

Cholangiocarcinoma

21
Q

Aflatoxin

A

hepatocellular carcinoma

22
Q

Vinyl chloride

A

Liver, angiosarcoma

23
Q

Carbon tetrachloride

A

liver, central lobular necrosis, fatty change

24
Q

Nitrosamines (smoked foods)

A

Gastric cancer

25
Q

Cigarette smoke

A

Larynx squamous cell carcinoma, lung squamous cell and small cell, renal cell carcinoma, bladder transitional cell carcinoma, pancreatic adenocarcinoma

26
Q

Asbests

A

Mesothelioma and Bronchogenic carcinoma

27
Q

Arsenic

A

squamous cell carcinoma of skin and liver angiosarcoma

28
Q

Naphthalene

A

bladder transitional cell carcinoma

29
Q

alkylating agents

A

leukemia

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