Tumors Misc Flashcards

1
Q

Tumor marker: PSA

A

prostate-specific antigen. Elevated in BPH and prostatitis. Questionable risk/benefit for screening

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2
Q

Tumor marker: Bombesin

A

Neuroblastoma, lung and gastric cancer

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3
Q

Tumor marker: prostatic acid phosphatase

A

prostate carcinoma

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4
Q

Tumor marker: CEA

A

CarcinoEmbryonic Antigen. Nonspecific but produced in 70% of colorectal and pancreatic cancers.

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5
Q

Tumor marker: a-fetoprotein

A

normally made in fetus. Hepatocellular carcinoma. Nonseminomatous germ cell tumors

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6
Q

Tumor marker: B-hCG

A

Hydatiform moles and choriocarcinomas, Associated with pregancy

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7
Q

Tumor marker: CA-125

A

ovarian cancer

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8
Q

Tumor marker: S-100

A

melanoma, neural tumors, schwannomas

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9
Q

Tumor marker: alkaline phosphatase

A

metastase to bone, liver, pagets disease of bone.

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10
Q

Tumor marker: trap

A

Hairy Cell leukemia (B cell)

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11
Q

Tumor marker: CA-19-9

A

Pancreatic adenocarcinoma

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12
Q

Tumor marker: Calcitonin

A

Medullary thyroid carcinoma

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13
Q

HTLV-1

A

Adult T-cell leukemia/lymphoma

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14
Q

HBV,HCV

A

Hepatocellular carcinoma

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15
Q

EBV

A

Burkitt’s lymphoma, Hodgkins lymphoma, nasopharyngeal carcinoma

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16
Q

HPV

A

Cervical carcinoma, penile/anal carcinoma, upper respiratory SCC

17
Q

HHV-8

A

Kaposi’s sarcoma

18
Q

H.Pylori

A

Gastric adenocarcinoma and Maltoma

19
Q

Schistosoma haematobium

A

Bladder cancer (squamous cell)

20
Q

Liver fluke (clonorchis sinensis)

A

Cholangiocarcinoma

21
Q

Aflatoxin

A

hepatocellular carcinoma

22
Q

Vinyl chloride

A

Liver, angiosarcoma

23
Q

Carbon tetrachloride

A

liver, central lobular necrosis, fatty change

24
Q

Nitrosamines (smoked foods)

A

Gastric cancer

25
Cigarette smoke
Larynx squamous cell carcinoma, lung squamous cell and small cell, renal cell carcinoma, bladder transitional cell carcinoma, pancreatic adenocarcinoma
26
Asbests
Mesothelioma and Bronchogenic carcinoma
27
Arsenic
squamous cell carcinoma of skin and liver angiosarcoma
28
Naphthalene
bladder transitional cell carcinoma
29
alkylating agents
leukemia