Common Chemotoxicities Flashcards
1
Q
Cisplatin/Carboplatin
A
nephrotoxicity(prevent with amifostine), acoustic nerve damage
2
Q
Vincristine
A
peripheral neuropathy
3
Q
Bleomycin, Busulfan
A
pulmonary fibrosis
4
Q
Doxorubicin
A
cardiotoxicity
5
Q
Trastuzumab
A
cardiotoxicity
6
Q
Cyclophosphamide
A
hemorrhagic cystitis
7
Q
5-FU
A
myelosuppression
8
Q
Methotrexate
A
Myelosuppression rescue with leucovorin(folinic acid)
9
Q
6-MP
A
myelosuppression
10
Q
Cytarabine
A
Leukopenia, thrombocytopenia, megaloblastic anemia
11
Q
Nitrosoureas (carmustine, lomustine, semustine, streptozocin)
A
CNS toxicity
12
Q
Vinblastine
A
Bone marrow
13
Q
paclitaxol
A
myelosuppression
14
Q
Etoposide
A
Myelosuppression, GI irritation, alopecia
15
Q
Hydroxyurea
A
Bone marrow suppression, GI upset
