Pharm Flashcards
What are some generic NSAIDs drugs?
Aspirin, diclofenac, indomethacin, ibuprofen, piroxicam, celecoxib
What is pharmacokinetics
The methods, by which drugs are absorbed, distributed, metabolize, and eliminated
What is the drug vechile
the substance in which a drug is transported
What is bioavailability
How completely a particular drug is absorbed by the system
What is the half-life of a drug
The rate of which a drug disappears from the body through metabolism, excretion, or both
What is the steady state of a drug
When the amount of the drug taken is equal to the amount that is excreted
What are bioequivalent drugs
Drugs that have similar biological effects
What are some serious complications of prolonged use of corticosteroids
Fluid and electrolyte disturbances, musculoskeletal and joint impairments, dermatological problems, neurological impairments, endocrine dysfunctions, ophthalmic conditions, and metabolic impairments
What is ergogenic aid
Any method, legal or illegal, used to enhance athletic performance
What should be done if an athletic trainer suspects a drug overdose
Call 911 and poison control
Why would a person want to blood dope
Endurance, acclimatization, and altitude make increased metabolic demands on the body, which responds to increasing blood volume and the number or red blood cells
What does dose-response relationship mean?
The relationship between the amount of substance and its overall effect on the body
Why is a dosing schedule important?
To avoid taking too little, which will not be effective, or too much that may cause life-threatening side effects
Who should be called in the case of a toxic drug overdose?
Poison control center
T/F. If taken inappropriately, many medicines and vitamins can be poisonous and are capable of causing illness or even death.
True
What is the therapeutically inactive substance that transports the drug?
Drug vehicle
How completely a drug is absorbed by the system is referred to as what?
Bioavailability
A biotransformation refers to what?
Transforming a drug so it can be metabolized
The excretion of a drug is controlled primarily by what?
Kidneys
The rate at which a drug disappears from the body is referred to as what?
Half-Life
What determines how often a drug will be administered?
The drug’s steady state
The first time an athlete fails a drug test, the NCAA declares an athlete ineligible for how long?
One year
What makes up the “skeleton” of the drug?
Pharmacophore
What does SAR stand for?
Structure activity relationship
What is the molecule that is acted on by an enzyme?
Substrate
What is an exipient?
Agent added to a drug withou a therapeutic effect
Describe the difference between a local and a systemic drug.
Local - works right at the site of application. Systemic - absorbed throughout the whole body
_____describes the physiological processes of how the body acts on a drug.
Pharmacokinetics
_____describes the process of how a drug acts on the body.
Pharmacodynamics
Nsaids are used to treat _____ and _____ inflammatory conditions.
Acute and chronic
______ are used by individuals with asthma to relax bronchial spasms and expanded airways.
bronchodilators
Bioavailability
how completely a particular drug is absorbed by the system
Prostaglandin
acidic lipid in the body concerned with vasodilation and a histamine-like effect which is inhibited by aspirin
Pharmacokinetics
the method by which drugs are administered, distributed, metabolized, and eliminated
NSAIDs
nonsteroidal antinflammatory drugs
What is the half-life of a drug?
the time required for the amount or concentration of a drug in the body to drop to one-half of its original value
What does ADME stand for?
absorption, distribution, metabolism, excretion
What is considered a beta- lactam antibiotic?
Penicillin
What is a sign
an objectively measurable and observable phenomenon associated with a disease
What is the common drug to treat Asthma?
Albuterol
what is pharmacokinetics?
the method by which drugs are absorbed, distributed, metabolized, and eliminated
what is bioavailability ?
How completely a particular drug is absorbed by the system
what is efficacy?
a drugs capability of producing a specific therapeutic effect
What is potency?
The does of a drug required to produce a desired therapeutic effect
Generic name vs brand name
Generic name is the name for the active ingredient, brand name is the company that makes that drug
Common banned drugs?
Anabolic steroids, diuretics beta blockers Human growth hormones
