Pharm Flashcards

1
Q

Drugs approved for obesity

A

Orlistat
Phentermine/Topiramate
Naltrexone/Bupropion
Liraglutide
Semaglutide
Tirzepatide

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2
Q

Prophylaxis of migraine

A

Sodium valproate
Gabapentin
Topiramate

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3
Q

Lennox gestaut syndrome

A

Sodium valproate
Lamotrigene
Topiramate
Rufinamide
Lacosamide

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4
Q

Antidote for dabigatran (DTI)

A

Idarucizumab

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5
Q

Antidote for Riveroxaban & Endoxaban
(Xa)

A

Andexanet alpha

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6
Q

Ciraparantag

A

Nonspecific antidote for
Heparin
LMWH
Direct thrombin inhibitor
Direct Xa inhibitor

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7
Q

Antidote for
Fondaparinux
Fondabiotaparinux

A

No inhibitor
Avidin

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8
Q

Treatment for ergotism

A

Sodium nitroprusside
CCB

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9
Q

Thiazide given in low GFR <30ml/hr

A

Metolazone
(Loop diuretics are safer)
(Thiazides cause ↓volemia ↓K+)

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10
Q

Off label uses of risperidone

A

OCD
PTSD
Bipolar disorder

Causes & C/I in dementia

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11
Q

Approved uses of risperidone

A

Schizophrenia
Abnormal behaviour
Tics

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12
Q

Adverse effects of Linezolid

A

Abdominal pain
Serotonin syndrome
Lactic acidosis
Myelo suppression
Peripheral & optic neuropathy

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13
Q

Drugs causing hypoprothrombinemia

A

Cefaperozone
Cefamendole
Ceftamet

Contains methyl tetra thiazole ring

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14
Q

A/E of Hydralazine

A

SLE

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15
Q

A/E for Aliskiren

A

Hyperkalemia

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16
Q

A/E for Verapamil

A

Constipation
Bradycardia

17
Q

OHAs causing fracture

A

Gliflozin

18
Q

Therapeutic index

A

LD 50 / ED 50

19
Q

A/E for Emtricitabine

A

Palm and sole pigmentation

20
Q

A/E for Zidovudine

A

Skin and nail pigmentation

21
Q

A/E for Nevirapine

A

Skin rashes
Hepatotoxicity

22
Q

A/E for Abacavir

A

SJS
MI

23
Q

QT prolangation

A

Vardenafil

24
Q

A/E of sildenafil

A

PDE 6 inhibition - blue Halo effect
Colour vision defect

25
Q

Drugs causing erectile dysfunction

A

Thiazides
Spironolactone
Beta blockers
Digoxin
Cimetidine
Anti androgens
Ethanol