pH and buffers Flashcards
1
Q
What does small pKa mean?
A
strong acid since dissociates largely
2
Q
what happens at half neutralization point?
A
pH=pKa
3
Q
What are buffers?
A
weak acid + conjugate base or vice versa
4
Q
what happens when Conjugate base bigger than acid?
A
buffers added acid better
5
Q
what happens when Conjugate base smaller than acid?
A
buffers added base better
6
Q
what happens when conc. of conj. base= acid?
A
ph=pka
7
Q
What is intracellular buffering?
A
by phosphates and histidine side chain of proteins
8
Q
What is histidine?
A
only amino acid with pka= physiological pH
9
Q
What is extracellular buffering?
A
by BICARBONATE SYSTEM
10
Q
What does carbonic anhydrase catalyse?
A
formation of carbonic acid
11
Q
What does mastication/mechanical stimulation cause?
A
increase salivary flow rate
