Peripheral Vascular Diseases Flashcards
- Reynaud’s phenomenon symptoms
- Intermittent claudication
- Stroke
- fingers spasm, extremities turn to pale or blue, often in elderly
- cold feet, absent pulses, exercise ind. cramping pain
- HE , confusion, dizziness, blurred vision
Drug of choice against the prophylaxis of transient ischemic attack?
ASA 81mg CHEWABLE
Monitoring parameters of anticoagulants: Heparin, Warfarin and LMWH
INR and PT is monitored for warfarin, aPTT for heparin, where as for LMWH these tests are not effective
Drugs that Inc. INR of Warfarin due to intestinal flora
Acute alcohol, Cotrimoxazole, Metronidazole, Phenylbutazone
Reynaud’s phenomenon- arteries of fingers become vasospastic
Give symptoms and from what conditions this results from and not
- symptoms: fingers spasm, extremities turn to pale, or blue
- result from atherosclerosis, connective tissue disease, ingestion of ergot alkaloids, or frequent use of vibrating tools
- NOT CAUSED BY PLAQUES
- Drug used to prevent PVD
- treat PVD
- CV drug least likely to treat PVD and why
- Warfarin
- Warfarin
- BB, causes vascular constriction, CI in PVD
OCP that have been withdrawn due to risk of blood clots in peripheral vascular system?
Yazmin
Risk factors of deep vein thrombosis (DVT)?
pregnancy, cancer and chemotherapy, Progestin only OCP, diabetes
can be used in tx of:
- DVT
- pulmonary embolism and DVT
Heparin: PE, DVT;
warfarin: PE, DVT, MI
streptokinase: DVT
Effects of warfarin include all except and give drug examples that does:
A. Decreasing the formation of blood clot
B. Nose bleeds
C. Red-orange urine
D. Ringing in the ears
Ringing in the ear is associated with ASA, salicylates, quinine, and quinidine, but not warfarin.
Explain how fresh frozen plasma immediately reverses anticoagulant effect of Warfarin toxicity
Warfarin inh. Vit K-dependent gamma-carboxylation of coagulation factors II, VII, IX and X, FFP replaces these factors that INR levels can be normalized quickly.
