Biochem Flashcards

1
Q
  • Glycine reaction is normally mediated by?

- responsible for nitric oxide (NO) in vivo?

A
  • Acetyl Coenzyme A

- Arginine

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2
Q
  • normal sodium serum in human body

- Potassium

A
  • 135-147 mEq/L

- 3.5-5 mEq/L

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3
Q

Folic acid has a tetrahydrofolate coenzyme activity based on what chemical structure?

A

-pteridine ring

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4
Q

What is correct regarding the formation of proteins?
A. Formed by condensation of peptide bond
B. Geometric sequence of amino acids
C. The formation occurs by complexation of a.a.

A

A

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5
Q
  • 1st precursor of vit A

- strongest endogenous pain producer in human body?

A
  • Carotene * Vitamin A is formed from retinoic acid that is formed from beta-carotene
  • Bradykinin
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6
Q

Biological catalysts responsible for supporting almost all of the chemical
reactions that maintain human life process:
A. Nucleic acid
B. Amino acids
C. Carbohydrates
D. Oligopeptides
E. Enzymes

A

E- Enzymes are proteins, catalyst because they are never altered during a reaction III- Michaelis-Menten theory describe the enzymatic reactions

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7
Q

Correct statements regarding mutation may include:
I- Cell division
II- Change in genotype
III- Change in DNA replication altering the gene

A

II and III

Mutation is a permanent transmissible change in the genetic material, usually in a single gene.

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8
Q

Shaped network present in the cell between nucleus and cell wall:

A

Endoplasmic reticulum:
Rough-protein synthesis
Smooth-lipid syn. Does not have ribosome

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9
Q

The Michaelis-Menten equation-Enzymatic reactions will appears ZERO order when:

A

When Km approaches Vmax

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10
Q

Hydrolysis of fixed oils may yields:

Explain

A

Glycerol + Fatty acids

Bc fixed oils and fats are esters of glycerol and fatty acids

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11
Q

In an enzymatic reaction, addition of competitive inhibitor leads to:
A. Increase the rate of reaction
B. Decrease the rate of reaction
C. Same rate of reaction
D. Decrease rate and increase substrate concentration
E. Decrease both rate and substrate concentration

A

C. does not alter reaction rate

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12
Q
All of the following can cause denaturation of proteins, except? A) acids
B) heating
C) bases
D) mechanical mixing
E) Buffers
A

E. Denaturising agents include: heat, organic solvents, mechanical mixing, strong acids or base, detergents and ions of heavy metals such as lead or mercury.

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