Endo. system Flashcards
Intracellular enzyme that generate free radicals include:
Superoxide desmutase
Free redicals
H2O2, benzoyl peroxide
not superoxide desmutase
Intra and extracellular ions
I: K, Mg, PO4
E: Na, Cl, Ca
A wasting due to lack of nutrition to a body part is
Atrophy
wasting is loss of function and tissue death
Secretion of corticoids
Adrenal cortex
What are the main risks associated with diabetes?
nephropathy, retinopathy, neuropathy, cardiopathy and GI conditions
Where are Erythropoietins released from and phgic role?
From kidney, helps in formation of RBC
Where is Oxytocin formed and stored?
formed in hypothalamus
stored in posterior pituitary gland
HRT is given to post menopausal women to prevent what? For how long?
Osteoporosis. 4 years
Steroid cylo-skeleton structures
3 cyclohexane and 1 cyclopentane
For PTU and MMI SAR, what functional group is essential for antithyroid activity?
Thioamide group
PTU and MIA MOA
Prevent the uptake of I by the gland they inhibit the synthesis of T3 and T4 by inhibiting the iodination of tyrosine in the thyroglobulin
Blocks the coupling of the iodo thyroxine
An asthma patient using prednisone 5 mg daily. Give possible SEs
ex: NOT dermatitis
hyperglycemia, fungal infx, weight gain, HTN
Which of the following conditions increase risk of lactic acidosis?
I) renal diseases
II) Liver diseases
III) excessive intake of alcohol
II and III
A patient reports to emergence with diabetic keto acidosis medical condition. What incorrect about diabetic ketoacidosis?
A. the major ketone is beta hydroxybutyric acid
B. it is mainly occurs in type 1 DM
C. Fruity smell is symptoms of diabetic ketoacidosis
D. diabetic ketoacidosis is NOT life threatening
E. diabetic ketoacidosis occurs due to severe hypoglycemia
E
