Peripheral Circulation And Regulation Of Flow Flashcards
what is the “regulator” for the autonomic system
medulla
final central pathway for modulation of sympathetic and parasympathetic drive is in the
medulla
baroreceptors are
stretch receptors located on the aortic arch and bifurcation of carotid
Parasympathetic pre ganglions are excited by
Increased baroreceptor input
B2 receptors in skeletal bed mediates
Vasodilation
Arterial chemoreceptors
Located on the aortic arch and bifurcation carotid artery - intermingled with baroreceptor ending
- are most sensitive to blood oxygen levels
Other short term cardiovascular reflexes
Cardiopulmonary reflexes
- atrial stretch receptors
-left ventricular receptors
Extrinsic reflex (pain and cold)
Atrial stretch receptors “low pressure baroreceptors”
Receptors located in the vent atrial junction
Afferents respond to sudden increasing in blood volume (inspiration, intravenous bolus)
Afferents travel via the vagus nerve to the NTA
Main reflex action is to increase heart rate
- little reflex change in TPR
Bainbridge reflex
Atrial volume receptors - increase heart rate - increased dieresis (water unloading) Through central pathways modulation of - selection changes in renal blood flow - changes in renal capacity for water reabsorption
Epinephrine has a higher affinity for
Beta 2 than alpha receptors
Norepinephrine has a higher affinity for
Alpha receptors
Angiotensin II and vasopressin
Normal circulating levels are low
Released during hypovolemia, dehydration and other disturbances to blood volume/osmolality
Short term vascular effects: potent vasoconstrictors via selective receptors on vasculature, high levels of circulating angiotensin II are associated with many forms of hypertension
Angiotensin has __ receptor subtypes: balance of activation
2