Perio etiology and therapy Flashcards
main etiologic bacteria for periodontal disease (aka chronic periodontitis)?
Porphyromonas gingivalis
etiologic pathogens for periodontitis are? Describe them
1) Porphyromonas gingivalis
- - virulence factors: fimbriae, hemaglutinin, capsular polysaccharide
2) Aggregatibacter actinomycetemomitans serotype B
- - fimbriae, PGA polysaccharide, serotype-specific carbohydrates, leukotoxin, proteases, cytolethal, GroEL-like protein
3) Tannerella forsythia
- - trypsin-like protease, sialidase, cysteine protease, apoptotic-inducing factor and lipoproteins
Streptococcus gordonii
early colonizers involved in plaque formation
streptococcus mutans
highly associated with caries
Lactobacillus casei
found in oral cavity (and intestines) and produces acid critical in enamel demineralization
main hormone associated with puberty and pregnancy associated gingivitis?
estrogen
sex hormones role in gingivitis?
sex hormones induce vasodilation and increases permeability along capillary walls. This allows more fluid to extravasate and cause severe inflammation
primary etiology of gingival inflammation?
plaque - bc bacterial aggregates from plaque initiate the inflammatory reaction
what is purulence composed of?
dead and dying neutrophils
streptococcus gordonii
- part of NORMAL oral flora
- in normal amounts it keeps balance between G- and G+ bacteria in mouth
- gram + cocci
- adheres to tooth pellicle
- considered one of the FIRST initial colonizers of dental biofilm by creating a site for bacteria to coaggregate
common causes of primary occlusal trauma?
over-filled dental restorations
crowns with high occlusion
heavy biting of hard substances
primary occlusal trauma VS secondary occlusal trauma
primary: trauma experienced by a tooth having NORMAL heathy periodontium
secondary: trauma experienced by a tooth with previous or COMPROMISED periodontium
* * MAY experience further trauma even if under normal occlusal loads
primary etiologic pathogen of localized aggressive periodontitis
Aggregatibacter actinomycetemomitans
1) first WBC to arrive at infected or injured tissue?
2) chronic infections include?
1) neutrophil
2) macrophages, lymphocytes and plasma cells
Treponema denticola
associated with necrotizing gingivitis/periodontits (ANUG/ANUP)
Actinomyces viscosus is associated with?
healthy gingiva
Most common viral oral infection?
Acute herpetic gingivostomatitis
Acute herpetic gingivostomatitis
commonly seen in children, viral
facultative anaerobes
can live with or without oxygen
- create their own energy source (ATP) via aerobic respiration through oxidative phosphorylation OR anaerobic respiration through fermentation
- require more energy to survive and make ATP fast
describe plaque after 48 hours
G+ cocci and rods (streptococcus and Actinomyces)
what two bacteria are associated with dental carries the most?
*streptococcus mutans** and Lactobacillus casei