Pericardial Diseases Flashcards
most common pericardial disease
acute pericarditis
define acute pericarditis (AP) and its common causes
inflammation of pericardium, usually viral or idiopathic, lots of other possibilities (post MI, TB, bacterial, uremia, PE, dresslers, drugs)
serous pericarditis
increased serous fluid from mesothelium
serofibrinous/fibrinous
inflammatory vasodilation, leakage of plasma proteins like fibrinogen
Bread and Butter, caused by virus, MI, SLE
suppurative/purulent pericarditis
inflammatory migration of PMNs
caused by bacteria
TB pericarditis
granuloma formation, caused by mycobacteria
signs/Sx of AP
prodrome of fever, malaise, myalgia
radiating chest pain, may be pleuritic, better sitting up than supine,
dyspnea, cough
AP physical exam
friction rub- heard at left sternal border, pretty specific scratching sound
heard during atrial systole, ventricle systole, and rapid ventricular filling
AP on ECG
4 stages: diffuse concave ST elevation and PR depression, then just PR depression, then T wave inverstion, then normal T waves
can also be low voltage and/or tachy
3 other findings w/ AP
maybe pericardial effusion, some myocarditis, signs of inflammation- WBC, ESR, CRP
managment of AP
hospitalize w/ unknown etiology, fear of effusion/tamponade, high risk
Tx w/ NSAIDs
AP outcomes
usually self limited, sometimes chronic or recurrent
some risk of constrictive pericarditis
define constrictive pericarditis
chronic inflamed pericardium- calcification and thickening
patho of CP
inhibits transmission of pressure into pericardial space, limits ventricle compliance (during mid to late diastole, still rapid early filling)
etiologies of CP
idopathic, viral, post op or radiation, infection- esp TB or purulent pericarditis, malignancy, trauma