Pericardial Disease - Acute Pericarditis Flashcards

1
Q

What is Acute Pericarditis?

A

Inflammation of the pericardium.

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2
Q

What is perimyocarditis (or myo-pericarditis)?

A

Pericarditis with inflammation extending into the myocardium.

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3
Q

Aetiology of Acute Pericarditis (7).

A
  1. Infections e.g. Cox-Sackie, TB.
  2. Uraemia - Renal Impairment : Fibrinous Pericarditis.
  3. Trauma.
  4. MI, Dressler’s.
  5. Connective Tissue Disease.
  6. Hypothyroidism.
  7. Malignancy.
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4
Q

Clinical Presentation of Acute Pericarditis (5).

A
  1. Pleuritic Chest Pain Relieved by Sitting Forwards.
  2. Non-Productive Cough.
  3. Dyspnoea.
  4. Pericardial Rub.
  5. Tachypnoea and Tachycardia.
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5
Q

Investigations in Acute Pericarditis (2).

A
  1. ECG.
  2. Transthoracic Echocardiogram (in all suspected cases).
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6
Q

What ECG changes can be seen in Acute Pericarditis? (3).

A
  1. Global/Widespread (not Territorial like MI).
  2. Saddle Shaped ST Elevation.
  3. PR Depression : Specific for Pericarditis.
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7
Q

What result is similar to ACS?

A

Troponin Rise.

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8
Q

How can ECG changes evolve over time? (3)

A
  1. 1-3 Weeks : Normalising of ST Changes and T Wave Flattening.
  2. 3-8 Weeks : Flattened T Waves become inverted.
  3. 8+ Weeks : ECG returns to normal.
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9
Q

Management of Acute Pericarditis (3).

A
  1. Treatment of Underlying Cause.
  2. Combination of NSAIDs and Colchicine 1st Line - Acute Idiopathic or Viral.
  3. Corticosteroids - 2nd Line : Non-Viral, Non-Infective.
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10
Q

When should caution be exercised with Colchicine use?

A

Renal or Hepatic Impairment.

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