Perfusion Flashcards
What does the pulmonary circuit include
?
right side of the heart, the pulmonary arteries, lungs, and the pulmonary capillaries
Why can an increase in pressure in the left side of the heart cause increased pulmonary vascular pressures and pulmonary edema?
Pulmonary veins have no valves and blood can back up into the lungs through the pulmonary veins
Which layer of a blood vessel prevents clotting and damage to blood cells?
tunica intima (specifically the smooth muscle in the endothelium)
Which layer of arteries is much thicker than veins?
tunica media
What is a major purpose of the pulmonary circuit?
Facilitate external gas exchange
What kind of system is seen in the systemic circuit?
a high-pressure system
Which blood vessel layer interfaces directly with the blood?
Tunica intima
The large arteries are able to adjust their size in response to the cardiac cycle for which reason?
An abundance of elastic fibers in the tunica media
Which atrium receives deoxygenated blood from the body?
Right atrium
Which atrium will receive oxygenated blood from the lungs?
left atrium
What is the innermost layer of the heart?
endocardium
What are the two layers of the pericardial sac?
parietal pericardium and visceral pericardium
What are the first vessels to receive CO after blood is leaving the left ventricle?
coronary arteries
Which coronary artery supplies the right ventricle?
right coronary artery
What does the left anterior descending artery supply?
the anterior aspect of the left ventricle and septum
What regulates the blood flow through the coronary arteries and the perfusion of the myocardium?
aortic pressure
The endocardium has which major function?
Provide a protective surface for direct exposure to blood cells
What is a unique property of cardiac muscle?
It has an abundant amount of myoglobin.
What is the major purpose of the heart valves?
Prevent the backward flow of blood
How is the term cardiac cycle best defined?
Heart muscle activities during one complete heartbeat
What does CI (cardiac index) take into account that CO does not?
BSA
4 determinants of CO
heart rate, preload, after load, and contractility
What is stroke volume?
the volume of blood pumped with each heartbeat
What is the stretch in the myocardial fibers at the end of diastole? And what does it represent?
preload, represents the volume of blood in the ventricle at the end of diastole
What is the Frank-Starling law of the heart?
the heart will pump the amount of blood it receives with each beat (until it meets the physiological limit)
The more the cardiac muscle is stretched during diastole, the stronger the contraction is during systole
What is afterload?
the resistance against which the ventricles must overcome to pump blood
the ventricular pressure after systole
What is Ohm’s law?
Pressure= Flow x Resistance
If calcium is increased, what will happen to the heart’s contraction?
it will result in a greater contraction
What are factors that influence contractility known as?
inotropes
If after load increases, stroke volume _____.
decreases
What is the measure of the percent of blood ejected with each stroke volume known as?
Ejection fraction