Cancer Flashcards
Which cancers commonly metastasize to the brain?
breast and lung
Which cancers commonly will metastasize to the lungs?
bladder, breast, lung (other lung), colon, ovary, pancreas, prostate, and uterus
Which cancers commonly metastasize to the peritoneum?
colon, ovary, pancreas, and uterus
What ratio of men will get cancer in their lifetime? And women?
1 in 2 men and 1 in 3 women
Why do geriatric patients get diagnosed with cancer in later stages more often?
cancer symptoms are often attributed to old age
7 warning signs of cancer (CAUTION)
Change in bowel/bladder habits
A sore that does not heal
Unusual bleeding or discharge from any body orifice
Thickening or a lump in the breast or anywhere else
Indigestion or trouble swallowing
Obvious change in wart or mole
Nagging cough or hoarseness
What are examples of primary prevention of cancer?
Decrease/eliminate exposure to carcinogens
Healthy diet
Exercise
Alcohol in moderation
Limit UV exposure (Sun/tanning beds)
What are examples of secondary prevention for cancer?
inspection, palpation, screening
What are the 3 goals of cancer treatment?
cure, control, palliation
What are 4 ways that cancer can be treated?
surgery, chemotherapy, radiation, and immunotherapy
What staging system is used for cancers?
TNM
Most common cancer site for women
Breast
Most common cancer site for men
Prostate
Which cancer causes the most deaths for men and women?
lung
Which type of lung cancer attributes to 80% of lung cancer deaths?
non-small cell lung cancer
What are the 5 main risk factors for lung cancer?
smoking, pollution, radiation exposure, asbestos exposure, exposure to industrial agents
Early manifestations of lung cancer
persistent cough, blood tinged sputum, dyspnea, wheezing, chest pain
Late manifestations of lung cancer
anorexia, fatigue, weight loss
What can an Xray visualize in a patient with cancer?
masses
What can a CT scan be used for in a patient with cancer?
location, lymph node enlargement, and involvement in other regions
What do an MRI, PET, Bone scan, CBC, and CMP assist in identifying in a cancer patient?
staging
What is the best cure for non small cell lung cancer?
surgical resection (stage I-IIIA only)
Risk factors for colorectal cancer
diet, lifestyle, history of IBD, heredity
Clinical manifestations of colorectal cancer
anemia, rectal bleeding, abdominal pain, change in bowel habits, tenesmus
What are diagnostic tests used for colorectal cancer?
flexible sigmoidoscopy, colonoscopy, CEA, FOBT
Which chemotherapies are often used to treat colorectal cancer?
5FU, Oxaliplatin
Which targeted therapies are often used to treat colorectal cancer?
Avastin, Erbitux
What is the largest risk factor for breast cancer in women?
age
Which ethnicity is at the highest risk for development of breast cancer?
African-American women
Why would a patient with and early menarche or late menopause be at a higher risk of developing breast cancer?
Prolonged exposure to unopposed estrogen
Clinical manifestations of early breast cancer
Skin changes, lumps, nipple discharge
What are clinical manifestations of metastatic breast cancer?
dyspnea, pain in back, confusion/altered LOC
What are the diagnostic tests used for breast cancer?
Mammography, U/S, Biopsy, HER2/hormone receptor status
Common chemotherapies used in breast cancer
cyclophosphamide, methotrexate, doxorubucin, paclitaxel
What are common treatments for hormone therapy in breast cancer patients?
tamoxifen, anastrazole, trastuzmab
What is the most common gynecologic cancer?
endometrial cancer
What are the 6 biggest risk factors for endometrial cancer?
Estrogen (unopposed)
Age
Nulliparity
Obesity
Smoking
Diabetes
What are common clinical manifestations of endometrial cancer?
abnormal uterine bleeding, pain
What is the second most common gynecologic cancer?
ovarian cancer
What are the 6 main risk factors for ovarian cancer?
BRCA gene
Nulliparity
Early menarche, late menopause
Obesity
Family history
Age