Pentose Phosphate Pathway

Question 1

What’s the other name for the pentose pathway?

Answer 1

Hexose Monophosphate Shunt

Question 2

Where does the pentose pathway occur?

Answer 2

cytosol

Question 3

Is the pentose pathway based on well fed or starved?

Answer 3

NEITHER

Question 4

What does the pentose pathway produce?

Answer 4

restores NADPH

helps form Ribose 5 phosphate

Question 5

Is NADPH similar to NADH or NAD?

Answer 5

NO!

it is a coenzyme

Question 6

What is the purpose of NADPH

Answer 6

reduct-biosynthesis

High energy to help form large and bulky molecules

Question 7

What is the function of the pentose pathway in the adrenal glands?

Answer 7

Steroid Synthesis

Question 8

What is the function of the pentose pathway in the liver?

Answer 8

Fatty Acid and cholesterol synthesis

Question 9

What is the function of the pentose pathway in the testes?

Answer 9

Steroid Synthesis

Question 10

What is the function of the pentose pathway in Adipose Tissue?

Answer 10

Fatty Acid Synthesis

Question 11

What is the function of the pentose pathway in the Ovaries?

Answer 11

Steroid Synthesis

Question 12

What is the function of the pentose pathway in the Mammary Glands?

Answer 12

Fatty Acid Synthesis

Question 13

What is the function of the pentose pathway in regards to RBCs?

Answer 13

Maintenance of reduced gluthathione

Question 14

What happens during the oxidative phase of the pentose pathway?

Answer 14

G6P
      NADPH + H
6 phosphoglucolactone 
      H+
6 phosphogluconate 
      NADPH + H
Ribulose-5-Phosphate

Question 15

What happens to G6P dehydrogenase when NADP+ levels rise?

Answer 15

increase ate

Question 16

What performs reductive fatty acid biosynthesis?

Answer 16

NADPH

Question 17

What performs reduction of hydrogen peroxide?

Answer 17

NADPH

Question 18

What performs to cytochrome p450 monooxygenase system?

Answer 18

NADPH

Question 19

What assists with phagocytosis by WBCs?

Answer 19

NADPH

Question 20

What aids with cholesterol biosynthesis

Answer 20

NADPH

Question 21

What assists with neurotransmitter biosynthesis?

Answer 21

NADPH

Question 22

What assists with Nucleotide biosynthesis?

Answer 22

NADPH

Question 23

Which two enzymes are used to fight free radicals?

Answer 23

Glutathione Reductase

Glutathione Peroxide

Question 24

Which 3 amino acids are in G-SH (Glutathione)

Answer 24

Glycine
Cysteine
Glutamate

Question 25

Which molecule fights H2O2 (hydrogen peroxide)? | What is the end product?

Answer 25

Glutathione | H20

Question 26

Which enzyme bypasses cell death when fighting H2O2?

Answer 26

Glutothione peroxide

Question 27

What is the purpose of Cytochrome p450 in the mitochondria?

Answer 27

participate in hydroxylation of steroids

Question 28

What is the purpose of Cytochrome p450 in the microsomal system?

Answer 28

associated with the membranes of the smooth endoplasmic reticulum (in liver) is the detoxification of foreign compounds (xenobiotics)

Question 29

Which system of phagocytosis by WBCs use pH changes in phagolysosomes and lysosomal enzymes to destroy pathogens?

Answer 29

Oxygen-independent system

Question 30

Which system of phagocytosis by WBCs includes the myeloperoxidase system and a system that generates oxygen-derived free radicals?

Answer 30

Oxygen-dependent system

Question 31

Which phagocytosis by WBCs is most potent of the bactericidal mechanisms?

Answer 31

MPO

Question 32

What traps bacteria in a phagocytic cell?

Answer 32

respiratory bursts

Question 33

What is the function of NO in regards to endothelium-derived relaxing factors?

Answer 33

cause vasodilation by relaxing vascular smooth mucle

Question 34

How does NO affect platlets?

Answer 34

promotes platlet aggregation

Question 35

What is NO main function?

Answer 35

macrophage function

Question 36

Which inherited disease is characterized by hemolytic anemia caused by the inability caused by the inability to detoxify oxidizing agents?

Answer 36

G6P Dehydrogenase Deficiency

Question 37

Why would someone with G6P Dehydrogenase Deficiency have a shortened life span?

Answer 37

complications with chronic hemolysis | RBCs have a shortened life span=shortened overal life

Question 38

On a microscopic scale, what is formed on RBCs when someone has G6P dehydrogenase deficiency?

Answer 38

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