Penicillin Flashcards
1
Q
Who discovered it and how
A
1928, Fleming
- left one of his dishes open to research cause of infection, when he returned from his holiday, he found mould on it and around it, Germs stopped growing
- but he couldn’t turn it into a drug so he wrote up his founding and left it
2
Q
Florey and chain
A
1930s, were interested in his research and were able to make powdered penicillin and tested it on mice
- then texted it on a human and kept him alive until it ran out
- they struggled to produce more (money) so WHEN US GOVERNMENT JOINED WW2 they gave them $80 million to make more
- this meant there was enough to treat all soldiers
3
Q
What did researched and companies do when penicillin was the first line of antibiotics
A
- produced thousands of new drugs
- this meant lack of control
- THALIDOMIDE was created as a sleeping pill for pregnant woman but could damage baby
- led to rougher regulations and testing of new drugs
4
Q
Problems with surgery
A
Although discoveries of Lister and Simpson improve surgery they did not understand blood groups
5
Q
Impact of WW1 on modern surgery
A
- WW1 was biggest and deadliest British had ever seen
- BLOOD TRANSFUSION, 1915, ‘blood banks’ were set up for battle casualties
- PLASTIC SURGERY, SKIN GRAFTS, as a result of fighting, many men had scars, GILLIES developed special hospital for army in 1917 for facial repairs, over 5000 were treated, could reconstruct faces
