PEDIGREE ANALYSIS Flashcards
show a record of the family of an
individua
Pedigree charts
They can be used to study the transmission of a
hereditary condition
PEDIGREE CHART
Aimed at determining the type of inheritance
pattern that a gene follows
PEDIGREE CHART
They are particularly useful when there are large
families and a good family record over several
generation
PEDIGREE CHART
Indicated by a solid horizontal
straight line connecting 2
individuals
o Married couple/Mating
Children
Indicated by a solid horizontal
that is connected to the
mating/married
_________s depicted as square and _________ as circle.
male and female
– unknown gender; it does not mean that
he/she is a transgender
Diamond
are identified by Roman numerals
GENERATIONS
numbered from the left
Arabic numerals
Person who is the focus of the pedigree
o The one who is being interviewed
PROBAND
- Indicated by an arrow and the letter P
PROBAND
Dominant type of trait would manifest even if it
would only appear on one allele.
AUTOSOMAL DOMINANT INHERITANCE
VARIOUS TYPES OF INHERITANCE
- Autosomal Dominant Inheritance
- Autosomal Recessive Inheritance
- Sex-linked Dominant Inheritance – Very Rare
- Sex-linked Recessive Inheritance – Very Rare
AUTOSOMAL DOMINANT INHERITANCE example
Polydactyly
o Huntington disease
o Neurofibromatosis
o Polycystic kidney disease
