Pediatric Tumors Flashcards
Signs/Symptoms of Bone Tumors & Bone Tumor-like Lesions
Persistent skeletal pain & swelling
Limitation of motion
Spontaneous fracture
Proceed with clinical, radiographic, lab & biopsy exam
Examples of Osteoblastic Connective Tissue Tumors
Osteoid osteoma
Osteosarcoma
Examples of Cartilage Tumors
Enchondromas
Chondromyxoid fibromas
Chondrosarcomas
Examples of Bone Tumors
Giant cell
Chondroblastomas
Ewing’s sarcoma
Things to Beware of
Night pain
Constant pain
Unusual symptoms
No improvement with conservative management
General symptoms
X-ray findings with lytic or blastic bone changes, soft tissue calcification or periosteal reaction
Unexplained mass
Evaluation of Pediatric Tumors
Physical exam
X-rays
Possible: bone scan, CT/MRI, chest x-rays/CT for high risk lesions
Consider: labs, consults/referrals
Biopsy of Tumor
Ideal if “ultimate” surgeon performing
Treatment of Clearly Benign Tumors
Observation vs. excision/curettage
Treatment of Possibly Malignant Tumors
Consider referral to regional cancer center
Who is all part of the team at regional cancer centers?
Pathologists Radiologists Surgeons Oncologists Radiation therapists
Classification of Tumors
Bony vs. soft tissue
Benign vs. malignant
Primary vs. metastatic
Epidemiology of Osteosarcoma
2nd most common primary bone tumor
High risk mets
Male = Female
Appendicular
X-ray Findings in Osteosarcoma
Mixed lytic/sclerotic lesions with cortical destruction
Epidemiology of Ewing’s
Highly anapestic
Long bone diaphyses
X-ray Findings in Ewing’s
Lytic, moth-eaten, indistinct margins, “onion skin”
Prognosis of Ewing’s with Pre-op Chemotherapy
Survival rate: 80-90%
Types of Resection with Soft Tissue Tumors
Intra-lesional
Marginal
Wide
Radical
Describe Soft Tissue Tumors
Small, superficial cystic lesions: benign/observed
Large, deep solid tumors: studies/biopsy
Different Classes with Soft Tissue Tumors
Fibrous Lipomatous Smooth muscle Striated muscle Vascular Synovial Neurologic