Pediatric Pulmonology Flashcards

1
Q

Chylothorax is a(n) […] pleural effusion due to disruption of lymphatic flow within the thoracic duct.

A

Chylothorax is a(n) exudative pleural effusion due to disruption of lymphatic flow within the thoracic duct.

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2
Q

Chylothorax is differentiated from other causes of exudative pleural effusion by its milky-white color and elevated […] levels.

A

Chylothorax is differentiated from other causes of exudative pleural effusion by its milky-white color and elevated triglyceride levels.

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3
Q

Congenital diaphragmatic hernia is associated with pulmonary […].

A

Congenital diaphragmatic hernia is associated with pulmonary hypoplasia.

may manifest as polyhydramnios on prenatal ultrasound

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4
Q

Cystic fibrosis may be differentiated from kartagener syndrome by the presence of pancreatic […].

A

Cystic fibrosis may be differentiated from kartagener syndrome by the presence of pancreatic insufficiency.

e.g. poor growth, deficiency of fat-soluble vitamins; both syndromes may cause recurrent sinopulmonary infections, digital clubbing, and nasal polyps

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5
Q

Cystic fibrosis may cause […] in men due to absence of the vas deferens.

A

Cystic fibrosis may cause infertility in men due to absence of the vas deferens.

accumulation of inspissated mucus in the fetal genital tract impairs development of the vas deferens

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6
Q

Cystic fibrosis may cause infertility in men due to absence of the […].

A

Cystic fibrosis may cause infertility in men due to absence of the vas deferens.

accumulation of inspissated mucus in the fetal genital tract impairs development of the vas deferens

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7
Q

Empiric treatment of pneumonia in a young child with cystic fibrosis should include coverage against […].

A

Empiric treatment of pneumonia in a young child with cystic fibrosis should include coverage against methicillin-resistant S. aureus.

e.g. IV vancomycin

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8
Q

In patients with subcutaneous emphysema secondary to severe cough paroxysms, a CXR must be obtained to rule out […].

A

In patients with subcutaneous emphysema secondary to severe cough paroxysms, a CXR must be obtained to rule out pneumothorax.

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9
Q

Neonatal respiratory distress syndrome is associated with diffuse granularity of the lung with a “[…]” appearance on CXR.

A

Neonatal respiratory distress syndrome is associated with diffuse granularity of the lung with a “ground-glass” appearance on CXR.

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10
Q

Neonatal respiratory distress syndrome is associated with […] birth.

A

Neonatal respiratory distress syndrome is associated with premature birth.

surfactant production doesn’t begin until at least week 24 and and surfactant levels are insufficient until around week 35

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11
Q

Neonatal respiratory distress syndrome is respiratory distress due to inadequate […] levels.

A

Neonatal respiratory distress syndrome is respiratory distress due to inadequate surfactant levels.

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12
Q

The risk of neonatal respiratory distress syndrome may be reduced by administering maternal antenatal […].

A

The risk of neonatal respiratory distress syndrome may be reduced by administering maternal antenatal glucocorticoids.

stimulates fetal surfactant synthesis and secretion

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13
Q

The […] is an assessment of newborn vital signs following labor via a 10-point scale evaluated at 1 minute and 5 minutes.

A

The Apgar score is an assessment of newborn vital signs following labor via a 10-point scale evaluated at 1 minute and 5 minutes.

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14
Q

Treatment of neonatal respiratory distress syndrome includes early […] +/- intubation.

A

Treatment of neonatal respiratory distress syndrome includes early positive pressure ventilation +/- intubation.

artificial surfactant may also be helpful

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15
Q

What is the likely diagnosis in an infant that presents with a scaphoid abdomen with bowel sounds heard over the left lung fields?

A

Congenital diaphragmatic hernia

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16
Q

What is the next step in management for a child in respiratory distress due to foreign body aspiration?

A

Bronchoscopy

characterized by sudden-onset respiratory distress; most aspirated foreign bodies end up in the right mainstem bronchus

17
Q

What is the next step in management for a child that presents with suspected anaphylaxis?

A

Intramuscular epinephrine

18
Q

What is the next step in management for a newborn with respiratory distress and hypoxia secondary to a suspected congenital diaphragmatic hernia?

A

Endotracheal intubation

ABCs take precedence over diagnostic studies; a gastric tube should be placed immediately after to decompress the stomach and bowel

19
Q

What is the recommended treatment for a child with a small parapneumonic effusion identified on X-ray with no respiratory distress?

A

oral antibiotics and outpatient follow-up

moderate or large effusions require drainage

20
Q

What is the recommended treatment for patients with croup and no stridor at rest?

A

oral corticosteroids + humidified air

21
Q

What is the recommended treatment for patients with croup and stridor at rest?

A

oral corticosteroids and nebulized epinephrine

22
Q

Which developmental pathology is characterized by bronchiectasis, recurrent sinusitis, and situs inversus?

A

Kartagener syndrome (primary ciliary dyskinesia)

an example of situs inversus is dextrocardia on CXR

23
Q

Cystic fibrosis is due to a defect in the […] gene on chromosome 7.

A

Cystic fibrosis is due to a defect in the CFTR gene on chromosome 7.

24
Q

Cystic fibrosis may cause malabsorption with […] and consequent […] vitamin deficiencies.

A

Cystic fibrosis may cause malabsorption with steatorrhea and consequent fat-soluble vitamin deficiencies.

deficiency of vitamin K may manifest as easy bruising and/or mucosal bleeding (e.g. epistaxis)

25
Q

Cystic fibrosis may cause […] cirrhosis and/or liver disease.

A

Cystic fibrosis may cause biliary cirrhosis and/or liver disease.

26
Q

Cystic fibrosis may cause […] insufficiency, resulting in malabsorption.

A

Cystic fibrosis may cause pancreatic insufficiency, resulting in malabsorption.

27
Q

Cystic fibrosis may cause […] in women due to abnormally thick cervical mucus and amenorrhea.

A

Cystic fibrosis may cause subfertility in women due to abnormally thick cervical mucus and amenorrhea.

28
Q

Cystic fibrosis most commonly occurs due to a deletion of […].

A

Cystic fibrosis most commonly occurs due to a deletion of Phe508.

29
Q

Is spermatogenesis possible in a patient with cystic fibrosis?

A

Yes

infertility in males with cystic fibrosis is due to absence of vas deferens, not lack of spermatogenesis

30
Q

Treatment of cystic fibrosis includes aerosolized […], which hydrolyzes DNA in mucus causing decreased viscosity.

A

Treatment of cystic fibrosis includes aerosolized dornase alfa (DNase), which hydrolyzes DNA in mucus causing decreased viscosity.

31
Q

Treatment of cystic fibrosis includes chest […], which aids in mucus clearance.

A

Treatment of cystic fibrosis includes chest physiotherapy, which aids in mucus clearance.

32
Q

Treatment of cystic fibrosis includes […], which is an antibiotic used as an anti-inflammatory agent.

A

Treatment of cystic fibrosis includes azithromycin, which is an antibiotic used as an anti-inflammatory agent.

33
Q

Treatment of cystic fibrosis includes […]-tonic saline, which facilitates mucus clearing.

A

Treatment of cystic fibrosis includes hyper-tonic saline, which facilitates mucus clearing.

34
Q

What is the mode of inheritance of cystic fibrosis?

A

Autosomal recessive