Pediatric Hematology Flashcards

1
Q

Neonates with this disorder present with isolated thrombocytopenia and absent radii with thumbs.

A

Thrombocytopenia Absent Radii (TAR)

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2
Q

True/False. Formula is a protective factor against iron-deficiency anemia as it is fortified with iron.

A

False - formula does not have iron. Babies who are exclusively breastfed are less likely to become iron deficient

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3
Q

What risk factor is most associated with folate deficiency in babies?

A

Exclusive goat’s milk consumption

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4
Q

Lead toxicity will cause what type of anemia?

A

Microcytic, hypochromic

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5
Q

What is the most common risk factor for the development of iron-deficiency anemia in infants?

A

Cow milk intake - especially before 1yo

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6
Q

True/False. Nucleated RBCs should not be seen in newborns.

A

False - nucleated RBCs are present until a week after birth

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7
Q

A newborn’s Hb levels will be (higher/lower) than adult levels at birth.

A

Higher - the fetus is in a relatively hypoxic state so increased Hb is needed

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8
Q

How are hemorrhagic disorders prevented in newborns?

A

Vitamin K injection at birth

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9
Q

What is the most common cause of anemia in children?

A

Iron Deficiency Anemia

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10
Q

What is the leading cause of death in adolescents with sickle cell disease?

A

Acute Chest Syndrome

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11
Q

True/False. Most pediatric cases of lead toxicity in the US are not severe and do not require intervention.

A

True - treatment is required when lead levels exceed 45mcg

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12
Q

This disorder is characterized by pancytopenia, absent thumbs, and an increased risk of leukemia.

A

Fanconi anemia

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13
Q

What is idiopathic thrombocytopenic purpura?

A

Destruction of platelets bound by antibodies. This often occurs after an acute viral infection

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14
Q

What is the most common cause of B12 deficiency in babies?

A

Exclusive breastfeeding by vegan mothers

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15
Q

What is physiologic nadir of infancy?

A

Occurs around 2 months, this is a low point in Hb (9-11) following birth before increasing

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16
Q

It is recommended that babies begin eating cereal around 6mo. Why is this?

A

Around 6mo, babies deplete the mother’s iron stores in breastmilk and receive less iron. Cereal is enriched with iron

17
Q

This is a disorder characterized by deficient RBC precursors and abnormal thumbs.

A

Diamond-Blackfan Syndrome