PCOS Flashcards
characteristic features of
multiple ovarian cysts infertility oligomenorrhoea hyperandrogenism insulin resistance
androgens
male sex hormones - testosterone
hirsutism
growth of thick dark hair often in a male pattern
Rotterdam criteria
2/3 of
- oligoovulation/anovulation presenting with irreg/absent periods
- hyperandrogenism - hirsutism and acne
- polycystic ovaries on USS
presentation
oligomenorrhoea/amenorrheoa infertility obesity hirsutism acne hair loss in male pattern insulin resistance
Ix - nice recommended blood tests
testosterone sex hormone binding globulin LH FSH prolactin TSH
hormonal analysis shos
raised LH
raised LH:FSH ratio
raised testosterone
raised insulin
LH and FSH levels
LH raised
LH raised more than FSH giving high ratio
gold standard for visualising ovaries
transvaginal USS
transvaginal USS - findings
string of pearls appearance
transvaginal USS - diganostic criteria
12+ developing follicles in one ovary
or
ovarian volume >10cm3
PCOS - screening test for diabetes
OGTT
OGTT results - impaired fasting glucose
fasting Gcl of 6.1-6.9
OGTT results - impaired glucose tolerance
plasma Glc at 2 hrs - 7.8-11.1
OGTT results - diabetes
plasma Glc at 2hrs >11.1