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Year 3 Exams: Endocrine > Pathology of Endocrine > Flashcards

Pathology of Endocrine Flashcards

1
Q

What gland regulates Basal Metabolic Rate?

A

Thyroid Gland

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2
Q

What gland produces calcitonin?

A

Thyroid Gland

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3
Q

Most common cause of Hyperthyroid?

A

Graves

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4
Q

Most common cause of Hypothyroid?

A

Hashimoto

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5
Q

What cells change in Hashimoto?

A

Hurthle

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6
Q

What happens to TSH in Multi Nodular Goitre?

A

Increases

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7
Q

What deficiency is most common cause of Multi Nodular Goitre?

A

Iodine

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8
Q

Follicular Carcinoma genes?

A

RAS Mutation or PAX8/PRRAG

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9
Q

Papillary Carcinoma genes?

A

BRAF Mutation or Ret/PTC

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10
Q

Primary Hypoparathyroid causes?

A

Adenoma

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11
Q

Pitutary Gland can be found where?

A

Sella Turcica

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12
Q

Anterior Pituitary secretes (6)

A 
ACTH
TSH
GH
Prolactin
FSH
LH
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13
Q

Posterior Pituitary secretes (2)

A

ADH

Oxytocin

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14
Q

How much function needs to be lost to classify pituitary hypofunction?

A

75%

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15
Q

Pituitary Hypofucntion can cause?

A

Sheehan Syndrome

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16
Q

Adrenal Gland medulla secretes what neuroendocrine cells?

A

Chromaffin Cells

17
Q

Conn’s Syndrome is also known as?

A

Bilateral Idiopathic Hyperplasia

18
Q

2 Degree Hyperaldosteronism causes what?

A

Increased Renin Angiotensin

Decreased Renal Perfusion

19
Q

Acute Adrenal Insufficiency can cause what two conditions?

A

Waterhouse Frederichsen

Meningoccal Septicemia

20
Q

How does Waterhouse Frederichsen present?

A

Hypovolaemic Shock

Hypoglycemia

21
Q

Chronic Adrenal Insufficiency is what two conditions?

A

Addisions

Congenital Hypoplasia

22
Q

Adrenal Medullary Tumours secrete what?

A

Catecholamines

23
Q

Catecholamines do what to blood pressure?

A

High Blood Pressure

24
Q

Adrenal Medullary Tumour Histology?

A

Nests Zellballen

25
Q

Men 1 is also known as?

A

Werner Syndrome

26
Q

Men 1 is closely linked to?

A

Defect in Menin Protein

Prolaitnoma

27
Q

Men 2 is closely linked to what gene mutation?

A

RET Proto Oncogene Mutation

Pituitary Adenoma

28
Q

MEN2A is also known as?

A

Sipple Syndrome

29
Q

MEN2b is autoactivation of what pathway?

A

Tyrosine Kinase Pathway

Year 3 Exams: Endocrine (34 decks)

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