Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Year 3 Exams: Endocrine > Cushings Syndrome > Flashcards

Cushings Syndrome Flashcards

1
Q

Cushings syndrome is caused by excess?

A

Corticosteroid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Cortisol is what type of hormone action?

A

Catabolic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What happens to insulin in Cushings?

A

Insulin Antagonism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Presentation of Cushings? (11)

A 
Skin Atrophy
Hypertension
Proximal Myopathy
Osteoporosis
Growth Arrest
Mooning
Hypokalaemia
Ostoepenia
Amenorrhoea
Hirtusim
Central Obesity
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Causes of Cushings? (5)

A 
Pituitary Tumour
ACTH Dependent
Ectopic ACTH
ACTH Independent
Corticosteroids
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Ectopic ACTH Dependent causes of Cushings? (1)

A

Lung Carcinoid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

ACTH Independent causes of Cushings? (2)

A

Adenoma or Carcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

ACTH Dependent causes of Cushings?

A

Cushings Disease/Pit Tumour

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Physiological Causes of Cushings (5)

A 
Pregnnacy
Glucorticoid Resistance
Depression
Obesity
Diabetes
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Diagnosis of Cushings (4)

A

24 Hour Urinary Free Cortisol
Overnight Dexamethasone Suppression
Plasma ACTH
MRI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What does Urinary Free Cortisol do in Cushings?

A

Increase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

If ACTH Decreases in Plasma ACTH what is the cause of Cushings?

A

ACTH Independent

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

If ACTH Increases in Plasma ACTH what is the cause of Cushings?

A

ACTH Dependent

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What treatment can be given for Cushings?

A

Surgery
Adrenal Hormone Synthesis Inhibitors eg ketoconazole, ecomidate, metyrapone
Destroy Adrenal Cells: Mitotone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What tablet can be given to destroy adrenal cells in cushings?

A

Mitotone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What adrenal hormone synthesis inhibitors can be given in cushings (3)

A

Ketoconazole
Ecotmidate
Metyrapone

17
Q

What 4 Side effects from Glucocorticoid use?

A

Lipolysis
Gluconeogenesis
Suppressed Immune
Protein Catbaolism

18
Q

Most Common Cause of Cushings Syndrome/Disease?

A

Pituitary Tumour

19
Q

Most Common ACTH Dependent reason for Cushings?

A

Pituitary Tumour

20
Q

What should overnight dexamethasone suppression test result be to confirm cushings?

A

> 50

Year 3 Exams: Endocrine (34 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions