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Year 3 Exams: Endocrine > Adrenal Disorders > Flashcards

Adrenal Disorders Flashcards

1
Q

Name a Mineralcorticoid?

A

Aldosterone

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2
Q

Name a Glucocorticoid?

A

Cortisol

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3
Q

Name two hormones produced by Medulla?

A

Epinephrine and Norepinephrine

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4
Q

Addisons Disease is it hypo or hyper secretion of Cortisol?

A

Hyposection

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5
Q

What happen to autoantibodies in Addisons?

A

Posterior Adrenal Autoantibodies to 21 Ohase

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6
Q

Which part of the Adrenal Gland is affected in Addisons?

A

Cortex

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7
Q

What three conditions are associated with Addisons?

A

Ovarian Failure
Thyroid Disease
Type 1 Diabetes

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8
Q

What happens to blood pressure in Addisons?

A

Hypotension

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9
Q

Unexplained Hypoglycemia happens in what Endocrine conditions?

A

Addisons Disease

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10
Q

What happens to periods in Addisons?

A

Amenorrhoea

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11
Q

How to Diagnose Addisons? (3)

A

Random Cortisol <50
Synacthen and Basal ACTH <450
Raised Plasma ACTH

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12
Q

What should random cortisol be below in Addisons?

A

50

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13
Q

What should Synacthen and Basal ACTH be below in Addisons?

A

<450

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14
Q

What three steroids to treat Addisons?

A

Hydrocortisone
Prednisolone
Dexamethasone

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15
Q

What treatment to use to replace mineralocorticoid in Addisons?

A

Fludocortisone

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16
Q

What is Fludocortisone’s actions in Addisons?

A

Binds to Aldosterone Receptors

17
Q

Fludocortisone dose in Addisons should be adjusted according to? (4)

A

Plasma Renin
Postural BP
Oedema
U+E

18
Q

When should special care be taken in Addisons?

A

Suppressed pituitary adrenal axis >7.5mg Prednisolone
Treatment during previous 18/12
Short Lived Illness
Major Illness

19
Q

How much prednisolone is enough to suppress pituitary adrenal axis?

A

> 7.5mg

20
Q

How to treat short lived illness in Addisons?

A

Glucorticoid x2

21
Q

How to treat major illness in Addisons?

A

Hydrocortisone

Year 3 Exams: Endocrine (34 decks)

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