Conn's Syndrome Flashcards

1
Q

What is Conn’s Syndrome?

A

Hypersecretion of Aldosterone

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2
Q

Conn’s Syndrome affects which part of Adrenal gland?

A

Cortex

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3
Q

What happens in Conn’s Syndrome Physiologically? (5)

A
Increased Blood Vol and Pressure
Increased Urine K+
Increased Aldosterone
Decreased Renin
Increased Aldosterone/Renin Ratio
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4
Q

What happens to Na+ Reabsorption in Conn’s Syndrome

A

Increased Na+ Reabsorb b y Distal Tubal and Collecting Duct of Nephron

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5
Q

What happens to K+ and H+ excretion in Conn’s Syndrome?

A

Increased

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6
Q

What happens to ECF Volume in Conn’s Syndrome?

A

Increased

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7
Q

Two main features of Conn’s Syndrome?

A

Hypotension and Hypokalaemia

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8
Q

What should the PA/PRA Ratio be in Conn’s Syndrome?

A

> 20

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9
Q

How to confirm diagnosis of Conn’s Syndrome (3)

A

24hr Urine Aldosterone >12
Urine Sodium >200
CT Adrenals

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10
Q

How does Conn’s Syndrome Present (4)

A

Hypertension
Hyperkalaemia
Decreased Renin
Increased Aldosterone

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