Conn's Syndrome Flashcards
What is Conn’s Syndrome?
Hypersecretion of Aldosterone
Conn’s Syndrome affects which part of Adrenal gland?
Cortex
What happens in Conn’s Syndrome Physiologically? (5)
Increased Blood Vol and Pressure Increased Urine K+ Increased Aldosterone Decreased Renin Increased Aldosterone/Renin Ratio
What happens to Na+ Reabsorption in Conn’s Syndrome
Increased Na+ Reabsorb b y Distal Tubal and Collecting Duct of Nephron
What happens to K+ and H+ excretion in Conn’s Syndrome?
Increased
What happens to ECF Volume in Conn’s Syndrome?
Increased
Two main features of Conn’s Syndrome?
Hypotension and Hypokalaemia
What should the PA/PRA Ratio be in Conn’s Syndrome?
> 20
How to confirm diagnosis of Conn’s Syndrome (3)
24hr Urine Aldosterone >12
Urine Sodium >200
CT Adrenals
How does Conn’s Syndrome Present (4)
Hypertension
Hyperkalaemia
Decreased Renin
Increased Aldosterone