Pathology of Development, Genetics and Ageing Flashcards
What is a congenital defect?
Defect present at birth
What is an inherited defect?
An inherited genetic abnormality
What is an acquired defect?
Non genetic defect determined by the environment
What is polygenic inheritance?
Lots of genes acting as a group spread all over the body
What is hypertrophy?
Increase in the size of tissue from increase in size of constituent cells
What is atrophy?
Decrease in tissue size from loss of size/number of constituent cells
What is metaplasia?
Change in differentiation from 1 cell –> another cell type
What is hyperplasia?
Increase in size of tissue from increase of number of constituent cells
What is dysplasia?
Morphological change in cells
What happens when a telomere gets too short to a cell
Stops dividing