Pathology - Breast Pathology Flashcards

1
Q

presentation of breast pathology

A

pain
lump
axillary node
nipple discharge/bleeding
nipple retraction
gynaecomastia
asymptomatic

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2
Q

bleeding from the nipple indicates what

A

intraductal papilloma

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3
Q

patient goes for screening mammography , mammography shows calcifications

what does this indicate

a.intraductal papilloma
b.ductal carcinoma in situ
c.fibroadenoma
d.invasive ductal carcinoma

A

b.ductal carcinoma in situ

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4
Q

investigations for symptomatic breast pathology

A

core biopsy- fragment of tissue (few days for results)

FNAC cells (results the same day )

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5
Q

FNAC is a biopsy of ..

A

cells

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6
Q

Core biopsy is a biopsy of …

A

tissue fragments

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7
Q

25 year old female with a painless lump
which scan is most useful

a.ultrasound
b.ct
c.ct pet
d.cxr

A

a.ultrasound

more useful in younger patients

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8
Q

25 year old female with a painless lump it is not tethered, ultrasound shows a well demarcated tumour a biopsy shows cells clustered together and cohesive
which diagnosis most likely ..

a.intraductal papilloma
b.ductal carcinoma in situ
c.fibroadenoma
d.invasive ductal carcinoma

A

c.fibroadenoma

discrete mobile lump
increase in size then plateau

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9
Q

55 year old hard, irregular palpable lump , 2.5 diameter spiculate appearance on CT what is performed to confirm diagnosis

a.FNAC
b.ultrasound
c.core biopsy

A

c.core biopsy

used to confirm diagnosis in malignant/suspicious lumps

then used to look for ER/PR/HER2

confirmed cancer

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10
Q

which type of breast cancer has a spiculate appearance

a.intraductal papilloma
b.ductal carcinoma in situ
c.fibroadenoma
d.invasive ductal carcinoma

A

d.invasive ductal carcinoma

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11
Q

55 year old hard, irregular palpable lump , 2.5 diameter spiculate appearance on CT , cells show they are separate and different appearances
what diagnosis most likely

a.intraductal papilloma
b.ductal carcinoma in situ
c.fibroadenoma
d.invasive ductal carcinoma

A

d.invasive ductal carcinoma

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12
Q

what is the most common type of breast cancer

A

invasive ductal carcinoma

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13
Q

carcinoma

A

lobular and ductal

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14
Q

in ductal carcinoma the cells have….. differntiation

A

glandular

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15
Q

in lobular carcinoma the cells do not have….. differentiation

A

glandular

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