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PLE 2018 > Pathology > Flashcards

Pathology Flashcards

1
Q

Most radiosensitive type of cervical cancer

A

Non keratinizing SCCA

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2
Q

Infiltration of fibrocartilaginous entheses with CD4+ and CD8+ T cells with high levels of TNF is seen in which rheumatologic condition?

A

Spondyloarthropathy

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3
Q

Rheumatologic condition characterized by pannus formation

A

Rheumatoid arthritis

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4
Q

Physiologic hyperplasia

A

Pubertal breast changes

Liver regeneration

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5
Q

Metaplasia

A 
Vit A deficiency (squamous metaplasia)
Myositis ossificans (connective tissue)
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6
Q

Most common cause of MR

A

MVP

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7
Q

Most common cause of MS

A

RHD

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8
Q

Most common cause of AR

A

Degenerative aortic dilatation

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9
Q

Most common cause of AS

A

Senile calcific aortic stenosis

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10
Q

Warthin-Finkeldey cells (MNGC with eosinophilic inclusions) are seen in

A

Measles

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11
Q

Diseases associated with MPGN Type 1

A 
SLE
Hep B and C
Endocarditis
Abscesses
HIV
Schistosomiasis
CLL
a1 antitrypsin def
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12
Q

Hallmark of chronic hepatitis

A

Portal inflammation

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13
Q

Fish mouth or buttonhole deformity and MacCallum plaques (subendocardial thickenings) seen in

A

RHD

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14
Q

Drugs causing decreased prod of platelet

A

Alcohol
Cytotoxic drugs
Thiazide

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15
Q

Drugs causing decreased platelet survival

A

Heparin
Quinidine
Sulfa drugs

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16
Q

Infections causing decreased prod of platelets

A

Measles

HIV

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17
Q

Infections causing decreased platelet survival

A

HIV
Infectious mononucleosis
Dengue fever

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18
Q

Diseases assoc with exogenous pigments (carbon)

A

Anthracosis

Coal worker’s pneumoconiosis

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19
Q

Sand-like lamellated concretions seen in papillary cancers

A

Psammoma bodies

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20
Q

Hallmark of malignancy

A

Anaplasia

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21
Q

Most common type of abnormality involving protooncogenes in human tumors

A

RAS

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22
Q

Exposure to benzene increases association with which cancer

A

AML

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23
Q

Exposure to cadmium increases association with which cancer

A

Prostate CA

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24
Q

Trosseau syndrome (venous thrombosis) is usually associated with which types of cancer

A

Pancreatic carcinoma

Bronchogenic carcinoma

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25
Q

Saturnine gout is seen in

A

Lead poisoning

26
Q

Itai - Itai disease is seen in what type of environmental poisoning

A

Cadmium

osteoporosis and osteomalacia with renal disease

27
Q

Integral membrane proteins defective in hereditary spherocytosis

A

Spectrin and ankyrin

28
Q

Triad of behcet’s disease

A

Recurrent aphthous ulcers
genital ulcers
uveitis

29
Q

Hofbauer cells are macrophages of what organ

A

Placenta

30
Q

Cyst formed from the remnant of Wolffian / mesonephric duct

A

Gartner duct cyst

31
Q

Most common cause of death in cervical CA

A

uremia

32
Q

most common malignancy of the female genital tract

A

endometrial carcinoma

33
Q

most important prognostic factor in endometrial CA

A

stage

34
Q

most common tumor in women

A

leiomyoma

35
Q

Most common primary malignant tumor of the ovary

A

Serous cystadenocarcinoma

36
Q

most common germ cell tumor

A

mature cystic teratoma

37
Q

Most common metastasis to the ovary

A

tumors of mullerian origin

urerus, fallopian tube, contralateral ovary, pelvic peritoneum

38
Q

Most common extramullerian metastasis to the ovary

A

breast and GI

39
Q

Schiller-Duval bodies are seen in

A

Yolk sac tumors

endodermal sinus tumor

40
Q

tumor marker for yolk sac tumors (endodermal sinus tumors)

A

AFP

41
Q

Call exner bodies are seen in

A

Granulosa cell tumors

42
Q

Flexner-Wintersteiner rosettes are seen in

A

Retinoblastoma

43
Q

Homer Wright rosette seen in

A

Medulloblastoma
Neuroblastoma
PNET

44
Q

Rosenthal fibers seen in

A

Pilocytic astrocytoma

45
Q

Blastema cells seen in

A

Wilm’s tumor

46
Q

Congo Red stain is used for

A

Amyloidosis

47
Q

Medullary thyroid cancer

Parathyroid hyperplasia

A

MEN 2A

Sipple’s disease

48
Q

Medullary thyroid cancer
Neuroma/Ganglioma
Marfanoid habitus

A

Men 2B

49
Q

Most common subtype of malignant melanoma

A

Superficial spreading

50
Q

Most common pneumoconiosis in the world

A

Silicosis

51
Q

Primary malignancies that commonly metastasize to the bone

A 
Prostate
Breast
Lung
Kidney
Thyroid
52
Q

most common cause of glomerulonephritis worldwide

A

IgA nephropathy

53
Q

most common benign tumor of the female breast

A

fibroadenoma

54
Q

virus that can cause hemorrhagic cystitis

A

adenovirus

55
Q

golden period for testicular torsion

A

6 hours

56
Q

most common etiology for acute and chronic bacterial prostatitis

A

E coli

57
Q

etiologic agents for chronic abacterial prostatitis (negative culture)

A

Chlamydia trachomatis
Mycoplasma hominis
Trichomonas
Ureaplasma

58
Q

most common symptom in prostatic adenocarcinoma

A

dysuria

59
Q

most common site of hematogenous spread of prostatic adenocarcinoma

A

bone

lumbar spine

60
Q

subtype of hodgkin’s lymphoma most associated with EBV

A

lymphocyte-depleted

61
Q

most common benign tumor of the liver

A

cavernous hemangioma

62
Q

Hallmark of acute inflammation

A

Increased permeability of postcapillary venules

PLE 2018 (12 decks)

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