Pathology Flashcards

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1
Q

Anatomic Pathologist

A

examines morphological (structural) changes in tissue and organs to examine cause of disease

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2
Q

Clinical physiologist

A

Examines change in blood (hematology and scrum chemistry) and tissue biopsy (cytology) to identify the cause of disease

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3
Q

Light Microscopy

A

Histology and Cytology
-Common diagnostic technique
-Light magnification to observe detailed tissue structure
-Various stains are used (to help identify and differentiate tissue structure

Resolution (ability to distinguish between two points): 200 um

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4
Q

Electron microscopy

A

-Improved resolution over the light microscope
-Electron beam used to provide tissue details
-Uncommon technique (older, not used for routine diagnostics)

Revolution: 1-200 um

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5
Q

What are the three types of electron microscopy?

A

-transmission EM
-scanning EM
-Scanning-transmission

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6
Q

Immunohistochemistry

A

Antibody binds to antigen

-Antibody is linked to a marker (fluorochloride of colour dye) – visualizing with microscope
-Common diagnostic technique

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7
Q

Polymerase Chain Reaction (PCR)

A

Polymerase Chain Reaction (PCR)
-Amplify segments of DNA: can amplify a single copy of DNA
-Commonly identifies: infectious agents, tumor biomarkers, and other genetic material
-Common diagnostic technique

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8
Q

Post Mortem examination (veterinary)

A

necropsy

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9
Q

Post Mortem examination (human)

A

Autopsy

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10
Q

What are the benefits of post-mortem analysis?

A

Common
Cost effective
Easy to perform (depends on skill of pathologist)

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11
Q

Paramixer virus (may be spelled wrong)

A

A virus that can transfer species (may be zoonotic)
ex. Canine distemper

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12
Q

Pathos

A

Suffering or disease

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13
Q

Logos

A

Study of

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14
Q

Morbidity

A

diseased state

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15
Q

Mortality

A

Death

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16
Q

Pathology

A

They study of disease

17
Q

Pathogenesis

A

The mechanism in which a sequence of events from a stimulus leads to a disease