pathologies related to ankle - exam 3 Flashcards
what is diabetes?
chronic systemic disorder characterized by hyperglycemia and abnormal metabolism
what is type I diabetes
- auto-immunity affecting the ______ that produces ______
- deficiency of ______
auto-immunity affecting the pancreas that produces insulin
deficiency of insulin production and secretion
what is type II diabetes
- excessive dietary _______ and ____ limits effect of insulin
- may be influenced by _______
- sugar and other simple carbs
- auto-immunity
what does insulin do?
released from the pancreas
lowers blood sugar
stores fat
incidence/prevalence of diabetes
- _______ of americans are pre-diabetic
- ______ americans have diabetes
- most common _______ disorder
- type _____ more common
1/3
1/10
endocrine/metabolic
II
Type I diabetes risk factor
presence of type I diabetes in first-degree relative
type II diabetes risk factors
family hx
ethnic origin
obesity
increasing age
physical inactivity
HTN
smoking
other contributers to diabetes
SAD
>/= 2 hours of screen time/day as part of sedentary lifestyle
daily carbonated beverage
fast food > 2x/week
unmanaged stress and lack of regular sleep
pathogenesis of type I diabetes
inability to produce and secrete adequate insulin to use glucose
pathogenesis of type II diabetes
- inadequate response of __
- increases:
- as cycle continues,
- _____ production stops
inadequate response of insulin receptors to insulin
increase: sugars, insulin, fat storage/inflammation
as the cycle continues, you limit the effect of insulin so body makes more insulin
insulin production stops –> obesity/diabetes develop
cardinal S&S of both types of diabetes
frequent urination (polyuria)
dry mouth
extreme thirst (polydipsia)
decreased skin turgor
blurry vision due to sugar damaging vessels
weakness/fatigue
excessive hunger
what are the sensory neuropathies that diabetes can progress to
- non-segmental paresthesia and hyposensitivity or numbness of involved peripheral n.
- joint destruction because repeated microtrauma is not felt (charcot foot)
- less aware of a heart attack they are already more prone to
what is the motor neuropathy diabetes can progress to?
weakness of mm. innervated by the involved peripheral n.
what is the autonomic neuropathies diabetes can progress to
affects function of multiple systems, particularly cardiovascular system
- diminished pulses
- necrosis
- poor healing
- stroke
- cardiac dz
other severe complications that could come from diabetes are:
- leading cause of ____ and _____
- _____ dysfunction leading to _______ (aka type III diabetes)
- kidney dz and blindness
- cognitive; Alzheimer’s
auto-immunity occurs with type _____
metabolic acidosis may occur with type _____
1
1
signs of diabetes:
- observation
charcot foot
dry mouth
cognitive decline
fruity and long deep breaths with TYPE I
signs of diabetes:
- scan & biomechanical exam
- neuro
- palpation
- age related joint change in 1/2 diabetics
- diminished sensation - peripheral n. pattern. assess 2 pt discrimination and monofilament sensation
(+) dural mobility
weaknesses of peripheral n
myotomes WNL (not affecting spinal n.) - palpation of diminished pulses
referral for diabetes
urgent