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PTHO > ✅Patho-Skin > Flashcards

✅Patho-Skin Flashcards

1
Q

Verrucae morphologu

A

Pappilomatous epidermal hyperplasia
Koilocytosis
Usually found on pressure areas

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2
Q

Molluscum bodies are large ellipsoid homogenous inclusions found in the

A

Stratum corneum and granulosum

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3
Q

Morphology of molluscum contagiosum lesions

A

Central umbilication

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4
Q

Etiology of impetigo contagiosa vs bullosa

A

Contagiosa GABHS

Bullosa s aureus

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5
Q

Morphology of impetigo

A

Subcorneal pustule

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6
Q

Urticaria and grouped vesicles found in those with celiac disease

A

Dermatitis herpetiformis

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7
Q

Morphology in dermatitis herpetiformis

A

Microabscesses and granular deposits of IgA at the tip of dermal papillae
Subepidermal blister

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8
Q

Loss of intercellular connections between keratinocytes

A

Acantholysis

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9
Q

Retention of nuclei in stratum corneum

A

Parakeratosis

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10
Q

Epidermal intercellular edema

A

Spongiosis

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11
Q

Maturation sequence of a melanocytic nevus

A 
Normal skin
Junctional nevus
Compiund nevus
Dermal nevus
Dermal nevus with neurotization
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12
Q

Morphology of dysplastic nevus

A

Lentiginous hyperplasia - replace the normal basal layer at the dermoepidermoid junction

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13
Q

Tumor progression sequence from dysplastic nevus to melanoma

A 
Lentiginous melanocytic hyperplasia
Lentiginous junctional nevus
Lentiginoua compound nevus
Early melanoma
Advanced melanoma
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14
Q

Most rapidly increasing cancer worldwide

A

Melanoma

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15
Q

2 growth phases of melanoma

A

Radial

Vertical

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16
Q

Most common type of melanoma

A

Superficial spreading melanoma

17
Q

Melanoma that occurs on sun exposed parts of the face

A

Lentigo maligna melanoma

18
Q

Melanoma that directly invades the dermis

A

Nodular melanoma

19
Q

Melanoma located on the palm sole or beneath the fingernails and common in blacks

A

Acral lentiginous melanoma

20
Q

Tumor depth staging in melanoma

A

Breslow thickness

21
Q

Increased number of seb ker in someone with GAstric adenoca

A

Leser trelat sign

22
Q

Morphology of seb ker

A

Basaloid cells with exuberant keratin production
Small keratin filled cysts (horn cysts)
Invaginations of keratin (invagination cysts)

23
Q

Morphology of acanthosis nigricans

A

Undulation of dermal papillae
Hyperkeratosis and basal cell hyperpigmentation
No melanocytic hyperplasia

24
Q

Cutaneous horn is found in

A

Actinic keratoses

25
Q

Most common invasive cancer in humans

A

Basal cell CA

26
Q

Morphology of actinic keratoses

A

Cytologic atypia
Dyskeratosis
Elastoses
Parakeratoses

27
Q

Morphology basal cell ca

A

Palisading pattern

Noduar and multifocal growth

28
Q

Erythema multiforme where erosions and crusts involve the lips and oral mucosa

29
Q

Targetoid lesions

A

Erythema multifome

30
Q

Psoriasis induced by local trauma

A

Koebnee phenomenon

31
Q

Pustules and abscess in psoriasis

A

Munro microabscesses - netrophils within the parakeratotoc stratum corneum

32
Q

Neutrophils in spongiotic foci of the superficial epidermis in psoriasis

A

Spongiform pustules of kagoj

33
Q

Itchy violaceous flat topped papules and plaques highlighted by white dots or lines in lichen planus

A

Wickhan striae

34
Q

Anucleate necrotic basal cells in lichen planus

A

Civatte or colloid bodies

35
Q

Morphology of lichen planus

A

Interface dermatitis
Sawtoothing of DE junction
Civatte or colloid bodies
Lichen planopilaris

36
Q

Positive nikolsky sign is seen in

Negative?

A

Pemphigus

Bullous pemohigoid

37
Q

Location of blister in
Pemphigus vulgaris
Pemohigus foliaceus
Bullous pemphigoid

A

Suprabasal
Subcorneal
Subepidermal

38
Q

Autoantibodies to _____are found in buklous pemphigoid

A

Hemidesmosomes

39
Q

Verrucae etiology

PTHO (34 decks)

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