patho of jaundice

Question 1

how is billirubin produced

Answer 1

mainly from the breakdown of RBCs and other proteins. It is highly toxic

Question 2

what is normal billirubin

Answer 2

.2-1.2 mg/dL about 0.2 is produced per day.

Question 3

what billirubin level is jaundice apparant

Answer 3

~2.5 mg/dL

Question 4

what is icterus

Answer 4

yellow discoloration of sclera due to hyperbillirubinemia

Question 5

what are the 3 components of bile

Answer 5

1. bilirubin
2. bile acids/salts
3. cholesterol

Question 6

how does cholestasis increase blood levels of bile componenets.

Answer 6

bile cannot get out of the gallbladder and it backups and start reguritating out into the blood stream.