Patho Final Exam Flashcards
Atherosclerosis
narrowing and hardening of arteries due to plaque build up
High blood pressure
diastolic-inability to fill ventricle
constriction or trapping of ventricle
hear is relaxed
systolic-lack of pumping strength of ventricle
back up of blood behind weakened ventricle
Atherosclerosis leading to chronic ischemia
heart is contracted
High blood pressure
diastolic-inability to fill ventricle
constriction or trapping of ventricle
systolic-lack of pumping strength of ventricle
back up of blood behind weakened ventricle
Atherosclerosis leading to chronic ischemia
Thrombophlebitis/deep vein thrombosis
blood clot or platelet that form in deep veins of the body usually in the legs or lower extremity
Angia pectoris
chest pain or chest discomfort seen in ischemic heart disease is related to having a heart attack occurs because lack of blood suppy to the heart
• Pain in neck , jaw, shoulder or chest
• Times of physical and emotional stress
Aortic Dissection
tearing or seperation of aortic walls which allow blood to get through to the aorta
Lymphedema
abnormal accumalation of high protein fluid forming just beneath the skin due to damage to lymph vessels or removal of the lymph nodes
shock
- low blood perfusion
- low blood pressure
cardiogenic-heart failure
hypovelimic- blood loss
septic-infection of the blood
anaphalctic shock-hypersensitivity reaction
Acute respiratory distress syndrome
what is it?
symptoms?
•Endothelial injury loss of fluids and proteins
Acute lung inflammation and diffuse alveolar capillary
• Sepsis and multiple trauma two common predisposed . Also pneumonia, near drowning , burns
• Characterized by severe hypoxemia
Multi-organ dysfunction syndrome
occurs during?
caused by?
- Failure of 2 or more systems due to injury or illness
- Leads to organ death, occurs during sepsis
- Caused by ischemia or impaired perfusion to organ from episode of shock or trauma
Disseminated Intravascular coagulation
why does this hapen
- Proteins that control blood clotting become overactive in blood vessels
- Not an illness, a complication
- Creates blood clots in many organs
- Normal clotting is disrupted as severe bleeding can occur
syncope
Occurs when?
- Loss of consciousness and posture
- Related to temporary insufficient blood flow to the brain
- When BP is too low and heart doesn’t pump oxygenated blood to brain
end stage renal disease
who is more commonly affected?
Symptoms?
As common as what?
- Final stage of kidney disease, kidneys are no longer functioning well enough to meet needs of daily life
- On dialysis
- Diabetics with high BP are more likely to be effected
- Decrease in urine output, inability to urinate, changes in skin color, excessive theist
- As common as heart attack
- Not in the end stage until your kidneys stopped working
Ascites
What is it?
What causes it?
Symptoms?
- Accumulation of fluid in the abdominal cavity most common cause of acid tights is advanced liver diseases or cirrhosis
- Occurs when the liver spots working
- Loss of appetite and shortness of breath
- Caused by liver scarring this increase pressure inside the liver is blood vessels
Temporal Arteritis
lack of blood supply to the head caused by narrowing or hardening of the arteries
- excessive sweating
- vision loss
- throbbing headache
- fatigue and weakness
Congestive Heart Failure Right vs. Left
Characteristics or symptoms
-left side stops working first followed by right side
-increased swelling in the abdomen
-left side pushes oxygenated blood and right side manages deoxygenated blood
-once failure gets to the right side you see severe pitting and edma
SYMPTOMS
-Diminished of pumping ability of left ventricle
-Back up of blood in the pulmonary vasculature
-Pulmonary edema-accumulation of fluid in air sacs of the lungs causing shortness of breath
-Peripheral edema-tissue swelling ususally in the lower limbs
lower legs sweating, perfus fluid loss
Arteriosclerosis
thickening and hardening of the arteries or blood vessels that affect blood flow
Congestive Heart Failure Right vs. Left
Characteristics or symptoms
-left side stops working first followed by right side
-increased swelling in the abdomen
-left side pushes oxygenated blood and right side manages deoxygenated blood
-once failure gets to the right side you see severe pitting and edma
SYMPTOMS
-Diminished of pumping ability of left ventricle
-Back up of blood in the pulmonary vasculature
-Pulmonary edema
-Peripheral edema
Myocardial Infarction
Heart attack
Cardiogenic heart failure -loss of pumping strength Arrythmias -Irritable electrical conduction Vascular dysfunction -Involvement of papillary muscles Rupture and tamponade
Arrythymias ( know each type and the prognosis ie. Ventricular tachycardia)
Abnormal heart rhythm or heart beat that can lead to death depending on severity of disease seen in myocarditis, myocardial infarction, and Ischemic heart disease
Cor pulmonale
Enlargement and failure of the right ventricle due to increased vascular resistance or high blood pressure in lungs
• Silent illness that leads to heart disease
Rheumatic Heart Disease
Scarring and stenosis of the Mitral and aortic valves
-old sites of inflammation of the myocardiium
scarring of the percarditits
Tetrology of Fallot
the inability of blood to flow to the lungs to receive oxygen that results in the flow of unoxygenated blood throughout the body
right ventricle hypertrophy- swelling up of ventricle due to heart working harder than normal
over-riding aorta- aorta lies between two ventricles, right sided unoxygenated blood flows directly into the aorta instead of the pulmonary vein
VSD- larger
stenosis of pulmonary tract or pulmonary vein
Vasculitis
inflammation of the blood vessels of the heart
-Changes in the walls of blood vessels including thickening weakening, narrowing and scarring these restrict blood resulting in organ and tissue damage
Polyarteritis nodosa
who is affected more?
Where is inflammation?
- Small and medium sized arteries become swollen and damaged
- Serious blood disorder
- Type of vasculitis
- More adults than children
- Inflammation throughout the whole arterial wall
Polyarteritis nodosa
- Small and medium sized arteries become swollen and damaged
- Serious blood disorder
- Type of vasculitis
- More adults than children
- Inflammation throughout the whole arterial wall
Chronic Obstructive Pulmonary Disease ( know each type throroughly
lasting longer than three months chronic cough with mucus production Air passage patency Increased resistance Acute -Asthma Chronic -chronic bronchitis -Emphysema
Aneurysm
An aneurysm is an abnormal widening or ballooning of a portion of an artery due to weakness in the wall of the blood vessel.
Chronic Obstructive Pulmonary Disease ( know each type throroughly
Air passage patency Increased resistance Acute -Asthma Chronic -chronic bronchitis -Emphysema
Restrictive Lung Disease
Ability of lung to expand
-decreased total lung capacity
Cystic fibrosis
- bronchial infections
- pancreas destruction
- thick mucous
Valvular diseases
stenotic (cant open all the way up)
Incompetent (cant close all the way)
Alpaha- 1 antitrypsin defeciency
- emphysema
- cirhossis
- cant neutralize activated proteases
Emphysema
Large airspace trapped in dilated alveoli causes compression of smaller airways Also hyperinflation -pink puffer -barrel chest -trapped air -rapid respirations -pursed lips
Asthma
What are the triggers
Bronchoconstriction
Type 1 hypersensitivity
IGE
Sensitization of CD4 cells Th2 cells release cytokines
Bronchiestasis
Dialated and inflamed bronchi repeat infections lots of mucous foul smelling breath unbelievable broductive morniing cough
Hyaline membrane formation
Initiation of inflammatory response
Neutrophils play a significant role
Oxidant injury
leakage of protein
chronic restrictive lung disease
- Occupational
- Chemotherapy
- Immunological
Occupational
-Asbestos
-Silicosis
Coal miners lung
Chemotherapy
-Busulfan
Immunological
- Rheumatoid arthritis
- sarcoid
- Scleroderma and other collagen vascular diseases
Vascular related pulmonary disease
syymptoms?
Acute alterations in blood flow -Congestion and edema -Pulmonary embolism Chronic congestion -Eisenmingers reaction
Pneumonia
Infection of the alveolar spaces -bacteria -TB Interestitial tissue -Virus Mycoplasma
Pleural tumors
Metastatic -about anywhere Primary, Mesothelioma -mesothelial cells -Abestos workers -Slow growing -Traps and invades lungs
Upper airway
-Allergic diseases
-Sinusitis
-Larynx
Infections
Polyps
Squamous cancer
Histoplasmosis
Symptoms
Breathing spores of diamorphic yeast and fungal growth often found in bird and bat droppings is a pulmonary infection
Chest pain. Chills. Cough. Fever shortness of breath
Fungal Pnemonias
What disease is common in this?
2 things?
Typically means something is wrong with the immune system Histoplasmosis is commom
- inhalation of spores
- Inhalation of Conidia
- reactivation of latent infections
Pulmonary Abscess
Aspiration of?
Hole with?
- Staphyloccoccus
- Aspiration of gastric material
- Hole with air fluid
Hyaline membrane formation
injury?
proteins?
Initiation of inflammatory response
Neutrophils play a significant role
Oxidant injury
leakage of protein