Path: Bone: 2 Flashcards
Bone and Soft tissue tumors more often benign or malignant
benign by far
For bone and soft tissue sarcomas,what is extremely important for px
HISTOLOGIC GRADE
Kids vs. adults: who has more malignant tumors
adults
5 tumors that frequently mets to bone (and mnemonic)
Prostate, breast, thyroid, lung, kidney (PT Barnum Loves Kids)
ALL sarcomas of bone and soft tissue metastasize to what organ more than any other organ
lungs
Are blastomas malignant or benign
benign
What does grade mean?
Grade: degree of differentiation
What location i smore often beingn: peripheral or central
peripheral
What 4 sarcomas display Lymphatic spread:
i. Synovial sarcoma
ii. Epithelioid sarcoma
iii. Rhabdomyosarcoma
Pedriatric sarcomas
Treatment of soft tissue tumors
Benign:
observe, surgical excision
Which 2 sarcomas respond to chemo only?
Rhabdomyosarcoma
Synovial sarcoma
What 4 pre-existing conditions cause soft-tissue tumore
i. Paget disease
ii. Infarcts
Radiation injury
Immunosuppresion
Kaposi sarcoma is caused by what
HHV-8
EBV causes what kind of tumors
EBV- smooth muscle tumors
marker: Ewing’s sarcoma:
t(11;22),