Past paper pop quiz 4 Flashcards

1
Q

How do the 2 forms of systemic sclerosis differ?

A

Limited: face + limbs distal to knees + elbows ‘CREST’
Diffuse: entire body

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2
Q

What are the features of limited systemic sclerosis?

A
Calcinosis
Raynaud’s phenomenon
oEsophageal dysmotility
Sclerodactyly
Telangiectasia
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3
Q

How does a tension pneumothorax arise?

A

When damaged area of pleura forms a 1-way valve resulting in the progressive accumulation of air in the pleural space

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4
Q

What is a positive Brudzinskis sign?

A

Passive flexion of neck causes involuntarily flexion of hip.

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5
Q

What is a positive Kernigs sign?

A

Lying supine, with hip flexed + knee flexed at 90 degrees to the hip joint.
Passive extension of knee causes pain

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6
Q

What 2 signs may be seen in MS?

A

Uhthoff’s sign: Worsening of neuro symptoms when body is overheated
Lhermitte’s sign: flexion of the neck causes a shooting pain running down the spine.

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7
Q

How are haemodynamically unstable patients in AF treated, irrespective of the time of onset?

A

DC cardioversion.

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8
Q

How are stable patients with AF presenting within 48 hours of onset treated?

A

DC cardioversion or chemical cardioversion

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9
Q

How are stable patients with AF presenting >48 hours since onset be treated?

A

Anticoagulation, using LMWH followed by warfarin, for > 3 weeks before elective cardioversion.

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10
Q

Name 2 drugs that can be used for chemical cardioversion

A

Flecainide- contraindicated in those with hx of IHD

Amiodarone.

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11
Q

Describe the pattern of features in MEN2a. What acronym can be used for this?

A

Thyroid: Medullary thyroid cancer
Adrenal: Phaeochromocytomas
Parathyroid hyperplasia
TAP

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12
Q

What could you investigate if you suspected a Phaeochromocytoma?

A

24 hr urine metanephrines

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13
Q

Which virus is implicated in ~50% of cases of Hodgkin’s lymphoma

A

EBV

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14
Q

List 6 causes of a high SAAG

A
Portal HTN
Cirrhosis
Constrictive pericarditis
Congestive cardiac failure
Budd-Chiari syndrome
Hepatic venous obstruction
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15
Q

List 5 causes of a low SAAG

A
Nephrotic syndrome
Malignancy
Pancreatitis
Infection
Bowel obstruction
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16
Q

What are the lower urinary tract symptoms?

A
FUN (storage/ irritative) WISE (Voiding/ obstructive)
Frequency
Urgency
Nocturia
Weak stream
Intermittency
Straining
incomplete Emptying
17
Q

Name 2 causes of a prolonged PT

A

Warfarin (depletion of factors II, VII, IX + X)

Liver disease

18
Q

Name 3 causes of a prolonged APTT

A
Heparin
Haemophilia A (factor VIII)
Haemophilia B (factor IX)
19
Q

What clotting results are seen in haemophilia A and B?

A

Prolonged APTT

Normal PT

20
Q

Give 2 indications of a ruptured abdominal aortic aneurysm

A

Sudden-onset flank pain

Features of circulatory collapse (e.g. tachycardia + hypotension)

21
Q

In a patient with perforated diverticulitis what is the most appropriate procedure?

A

Hartmann’s procedure
Removal of sigmoid colon with formation of a rectal stump + end colostomy.
Allows time for inflammatory process to resolve + can be reversed, forming an anastomosis.

22
Q

What condition may present with paresis, weakness, sensory loss, sphincter dysfunction and erectile problems?

A

Spinal cord compression

23
Q

How can you distinguish between acute cord compression (Cauda equina) and gradual cord compression (spinal stenosis)?

A

Acute: LMN signs
Gradual: UMN signs

24
Q

What mnemonic can be used to remember the major criteria for rheumatic fever?

A

JONES:
Joints (arthritis)
O – looks like a heart (carditis e.g. tachycardia, murmurs)
Subcutaneous Nodules
Erythema marginatum (a rash with red, raised edges + clear centre)
Sydenham’s chorea (involuntary semi-purposeful movements)

25
Q

What is rheumatic fever usually caused by?

A

Streptococcus pyogenes

26
Q

Where do testicular tumours spread? What symptom may this occasionally cause?

A

Para-aortic lymph nodes

may cause backache

27
Q

Define the parameters for type 1 and type 2 respiratory failure?

A

Type 1: PaO2 < 8 kPa, PaCO2 = normal

Type 2 = PaO2 < 8 kPa + PaCO2 > 6 kPa

28
Q

What is an anal fissure?

A

Painful tear in squamous lining of lower anal canal

29
Q

Give 4 features of an anal fissure?

A

Pain on defecation
Bright red blood streaked on toilet paper/ stools but not mixed in with the stools.
Low fibre diet
Poor fluid intake
(May be constipated + strain at the stool)

30
Q

What triad characterises Felty’s syndrome?

A

Rheumatoid arthritis
Splenomegaly
Neutropenia

31
Q

In a hyponatraemic patient, what is a major consequence of raising plasma sodium concentration too rapidly?

A

Central pontine myelinolysis

Myelin cells dont have enough time to adapt to increasing extracellular osmolality, draws water out of the myelin cells

32
Q

What acronym can be used to remember the drugs indicating need for dialysis in the “intoxication” part of AEIOU?

A
BLAST
Barbituates
Lithium
Alcohol
Salicylates
Theophyline