DPD: Amir Sam Neuro cases Flashcards
Which sites may a lesion causing a neurological pathology be found?
Brain Spinal cord Nerve roots Peripheral nerves Neuromuscular junction
What may cause neurological pathology broadly speaking?
Vascular Infection Inflammation/ AI Toxic/ Metabolic Tumour/ malignancy
State what would be affected by pathology of each of the cranial nerves
I: sense of smell II: VA, VF, pupils, fundoscopy III, IV, VI: diplopia V: sensation, corneal reflex VII: facial palsy VIII: hearing IX, X: Speech, swallowing XI: Sternocleidomastoid, trapezius XII: tongue movements
Describe the tone, power and reflexes seen in upper motor neurone lesions
Tone: Increased (spasticity)
Power: Decreased
Reflexes: Increased (brisk), upgoing plantar
Describe the tone, power and reflexes seen in lower motor neurone lesions
Tone: Decreased (flaccid)
Power: Decreased
Reflexes: Diminished
List 3 examples of UMN conditions
Stroke
Multiple sclerosis
Huntingtons disease
Using the acronym, list the cerebellar signs
Dysdiadochokinesa Ataxia Nystagmus Intention tremor Slurred/ staccato speech Hypotonia
How would you locate the lesion based on the distribution of abnormal sensation?
Cerebral cortex: Hemisensory loss Spinal cord: reduced up to certain Level Nerve roots (Radiculopathy): Dermatome Mononeuropathy: Specific area Polyneuropathy: Glove + stocking
Considering the broad causes of pathology, what can cause peripheral neuropathy?
Vascular: No.
Infection: HIV
Inflammation/ AI: Vasculitis, CTD, inflammatory demyelinating neuropathy
Toxic/ Metabolic: DM, Alcohol, B12 deficiency
Tumour/ Malignancy: Paraneoplastic feature
Give 3 features of papillitis (optic neuritis at head of optic nerve)
Blurred vision
Blurred optic disc margins
Pain on eye movement
What features are suggestive of MS?
2 lesions
Separated in time + space
Give 4 differentials for apparent confusion and decreased AMTS
Post-ictal (post seizure)
Dysphasia
Dementia
Depressive pseudo dementia
Describe the GCS
Eyes 4 = Spontaneous 3 = Opens in response to voice 2 = Opens in response to painful stimuli 1 = Does not open
Verbal response 5 = Oriented 4 = Confused 3 = Words 2 = Sounds 1 = No sounds
Motor response 6 = Obeys commands 5 = Localizes pain 4 = Withdraws to painful stimuli 3 = Abnormal flexion 2 = Extension 1 = No movements
List the 10 components of AMTS
DOB Age Time Year Place Recall (West Register Street) Recognize doctor + nurse PM/ Monarch Date of 2nd WW Count backwards from 20 to 1
Give 3 signs of meningitis
Fever
Neck stiffness
Kernig’s sign