Passmed Rheumatology - Pharmacological Managements Flashcards

1
Q

Ankylosing spondylitis

A

NSAIDs
Anti-TNF in rare cases

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2
Q

Anti-phospholipid syndrome

A

Primary prophylaxis = low-dose aspirin
Secondary prophylaxis = lifelong warfarin INR 2-3, if recurrent VTE INR 3-4

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3
Q

Azathioprine

A

Bone marrow suppression + pancreatitis
Don’t use with allopurinol
Safe in pregnancy

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4
Q

Gout

A

Acute = NSAID or colchicine, oral/intra-articular steroid if peptic ulcer disease
Chronic = allopurinol with initial colchicine cover

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5
Q

Hydroxychloroquine

A

Retinopathy
Safe in pregnancy

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6
Q

Osteoarthritis

A

1st - Paracetamol +/- topical NSAID (if knee or hand)
2nd - oral NSAIDs/COX-2 inhibitors
Can also consider opioids, IA steroids, capsaicin cream

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7
Q

Osteomalacia

A

Vit D supplementation +/- calcium supplementation if needed

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8
Q

Osteoporosis

A

Alendronate
If can’t tolerate = risedronate or etidronate
If can’t tolerate = strontium ranelate, raloxifene

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9
Q

Paget’s disease of the bone

A

Oral risedronate or IV zoledronate

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10
Q

Polymyalgia rheumatica

A

Oral prednisolone

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11
Q

Reactive arthritis

A

Analgesia
NSAIDs
IA steroids

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12
Q

SLE

A

Hydroxychloroquine

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13
Q

Temporal arteritis

A

No visual loss = oral high-dose prednisolone
Visual loss = IV methylprednisolone

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14
Q

Sulfasalazine

A

Myelosuppression, oligospermia
Safe in pregnancy + BFing

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