Passmed Pharmacology Qs + Principles Flashcards

1
Q

Side effects of metformin?

A

GI side-effects
Lactic acidosis

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2
Q

Side effects of sulfonylureas?

A

Hypoglycaemia
Increased appetite + weight GAIN
SIADH
Cholestatic liver dysfunction

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3
Q

Side effects of glitazones?

A

Weight GAIN
Fractures
Fluid retention
Liver dysfunction

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4
Q

Main notable side effect of gliptins?

A

Pancreatitis (remember the P’s)

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5
Q

Causes of serotonin syndrome?

A

STrEAM

St John’s Wort
Tramadol
Ecstasy
Amphetamines
MAOi

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6
Q

Management of serotonin syndrome?

A

Benzodiazepines

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7
Q

Trastuzumab side-effects and important baseline test?

A

Cardiotoxicity = cardiomyopathy (do echo before starting)
Flu-like symptoms + diarrhoea

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