Passmed Dermatology - Pharmacological Managements Flashcards

1
Q

Acne vulgaris

A

1st - topical retinoids/benzoyl peroxide
2nd - topical tetracycline
3rd - oral tetracycline or erythromycin if pregnant/BFing. COCP/Dianette also an alternative (max 3 months)
4th - oral isotretinoin

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2
Q

Actinic keratoses

A

Topical fluorouracil, 2-3 weeks, with topical hydrocortisone

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3
Q

Alopecia areata

A

Topical/intralesional steroids

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4
Q

Sedating vs Non-sedating antihistamines?

A

Sedating - chlorpheniramine
Non-sedating - loratidine, cetirizine (more drowsiness than other non-sedating)

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5
Q

Athlete’s foot

A

Topical imidazole

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6
Q

Bullous pemphigoid

A

Oral steroids

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7
Q

Eczema herpeticum

A

IV aciclovir

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8
Q

Erysipelas + cellulitis

A

Flucloxacillin

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9
Q

Fungal nail infection

A

Limited = topical amorolfine nail lacquer
Extensive dermatophyte = oral terbinafine
Extensive candida = oral itrazonazole

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10
Q

Hyperhidrosis

A

Topical aluminium chloride

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11
Q

Impetigo

A

1st - topical hydrogen peroxide
2nd - topical fusidic acid, mupirocin if resistant

Extensive = oral flucloxacillin, erythromycin IPA

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12
Q

Key safety point about ketoconazole?

A

Oral version is high risk for hepatic toxicity so virtually completely contraindicated
Topical version is fine due to low systemic absorption

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13
Q

Lichen planus

A

Potent topical steroid
Benzydamine mouthwash/spray for oral involvement
Extensive = oral steroids

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14
Q

Lichen sclerosus

A

Topical steroids + emollients

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15
Q

Drug that causes Pellagra?

A

Isoniazid

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16
Q

Pemphigus vulgaris

A

Steroids

17
Q

Pityriasis versicolor

A

1st - Ketoconazole shampoo
2nd - oral itraconazole

18
Q

Plaque psoriasis

A

1st - topical potent steroid + vit D analogue once daily
2nd - vit D twice daily
3rd - potent steroid twice daily OR coal tar OR dithranol

Steroids for max 4 weeks at a time

19
Q

Scalp and face/flexural/genital psoriasis

A

Scalp - topical potent steroid
FFG - topical mild/moderate steroid

20
Q

Rosacea

A

Flushing - Topical brimonidine
Papules/pustules - Topical ivermectin. Add oral doxycycline if moderate/severe

21
Q

Scabies

A

1st - Permethrin 5%
2nd - Malathion 0.5%

22
Q

Seborrheic dermatitis

A

Scalp - OTC zinc pyrithione/tar, topical ketoconazole
Face/body - topical ketoconazole

23
Q

Shingles

A

<72 hrs = aciclovir/famciclovir/valaciclovir
Pain relief = paracetamol/NSAIDs, neuropathic agent, steroid

24
Q

Drugs that cause toxic epidermal necrolysis?

A

SCAN PP
- sulphonamides
- carbamazepine
- allopurinol
- NSAIDs
- phenytoin
- penicillins

25
Q

Urticaria

A

Non-sedating antihistamine (cetirizine, loratidine)
Prednisolone if refractory

26
Q

Oral agent can give for peripheral vasodilation in venous ulcer?

A

Oral pentoxifylline