Passmed Endocrinology - Pharmacological Managements Flashcards
1
Q
Acromegaly
A
(surgery 1st line)
Octreotide
Bromocriptine
Pegvisomant
2
Q
Addison’s
A
Hydrocortisone 20-30mg per day, majority in first half of day
Fludrocortisone
Double hydrocortisone dose in illness/surgery
3
Q
Addisonian crisis
A
IV hydrocortisone 100mg, continue 6hrly until stable
4
Q
Graves disease
A
Carbimazole 40mg, titrate down for euthyroid
OR
Carbimazole 40mg, add thyroxine once euthyroid
5
Q
Major side effect of carbimazole therapy?
A
Agranulocytosis
6
Q
Hypothyroidism
A
Levothyroxine, aiming for normalisation of TSH
Avoid giving with iron/calcium carbonate (min 4 hrs apart)
7
Q
Prolactinoma
A
Dopamine agonist - bromocriptine, cabergoline
8
Q
Examples of SGLT-2 inhibitors
A
Canagliflozin, dapagliflozin, empagliflozin
