Passmed Gastroenterology - Pharmacological Managements Flashcards

1
Q

Acute upper GI bleed

A

Platelets if <50
FFP if fibrinogen/APTT deranged
Terlipressin + antibiotics

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2
Q

Alcoholic ketoacidosis

A

Infusion of saline + thiamine

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3
Q

Alcoholic hepatitis

A

Prednisolone

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4
Q

Ascites

A

Spironolactone
Prophylactic ciprofloxacin

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5
Q

Autoimmune hepatitis

A

Steroids

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6
Q

Bile acid malabsorption

A

Cholestyramine

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7
Q

Carcinoid tumours

A

Octreotide (somatostatin analogue)

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8
Q

H. pylori eradication

A

PPI + amoxicillin + clarithromycin/metronidazole (both if PA)

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9
Q

Prophylaxis of hepatic encephalopathy

A

1st - lactulose
2nd - add rifaximin

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10
Q

IBS symptom management

A

Pain - antispasmodic agents
Constipation - laxatives, avoid lactulose
Diarrhoea - loperamide

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11
Q

Peptic ulcer - acute bleeding

A

IV PPI

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12
Q

Primary biliary cirrhosis

A

Ursodeoxycholic acid
If itching = cholestyramine as well

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13
Q

Main adverse effects of PPIs (3)

A

Hyponatraemia, hypomagnesaemia
Osteoporosis
Increased risk of C. diff

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14
Q

Consequences of refeeding syndrome

A

Hypophosphataemia
Hypokalaemia
Hypomagnesaemia

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15
Q

How to prevent refeeding syndrome?

A

If haven’t eaten for >5 days, only re-feed at max 50% of requirements for the first 2 days

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16
Q

Spontaneous bacterial peritonitis

A

IV cefotaxime

17
Q

Wilson’s disease

A

Penicillamine