passage of an action potential Flashcards
what is an refractory period
period during which the membrane of the axon of a neurone cannot be depolarised and no new action potential can be intiated
why can’t neurone be stimulated straight away (after A.P) ?
- Na+ ion channel closed during repolarisation
- K+ ion channel closed during hyperpolarisation
why is the refractory period important
delaying time between one a.p and next
ensuring a.p pass as discrete impulses
AP travels in 1 direction from cell body to axon terminal
limiting the frequency of impulses transmitted
explain the passage of an action potential along an unmyelinated axon
- stimulus - Na+ ions move into the axon via voltage gated sodium channels
causing membrane to depolarise (Action Potential) - movement of action potential - Na+ ions diffuse sideways (forming localised electric current) causes the Na+ voltage gated channels to open further along the membrane causing the next section to become depolarised
- start of repolarisation - on reaching +30mV Na+ voltage gated channels close and K+ channels open and K+ moves out of axon while action potential moves along axon
- return to resting potential - Na+/ K+ pump restores membrane potential to -70mV
explain how an action potential travels along a myelinated neurone
- Na+ ion channels are concentrated at the nodes of Ranvier
- depolarisation occurs
- local current can only act at nodes of Ranvier so depolarisation only occurs at the nodes where Na+ ions can get through the membrane
what is the name of the conduction that takes place in a myelinated neurone
saltatory conduction
define saltatory conduction
action potential jumps from node to node of Ranvier as depolarisation only occurs at the nodes of ranvier
or
localised circuits occur between adjacent nodes and cause action potential to jump from node to node
define myelinate axon
wrapped in schwann cells
the layers of membrane act as an insulator increasing the speed of electrical transmission
myelin accelerates electrical impulses along the axon
define the refractory period
period during which the membrane of the axon of a neuron cannot be depolarised and no new action potential can be intiated
why can’t neurone be stimulated straight away after an action potential
- Na+ ion channels closed during repolarisation
- K+ ion channels closed during hyperpolarisation
what are the 4 reasons for why the refractory period so important
- delaying time between 1 action potential and the next
- ensuring action potentials pass as discrete impulses
- AP travels in 1 direction from cell body to axon terminal
- limiting the frequency of impulses transmitted
what is a node of ranvier
breaks in myelin sheath at intervals of 1-3 mm
action potentials only occur at this point