diabetes Flashcards
define biosensory
a device that uses biological molecules to measure level of certain chemicals
explain what happens when blood glucose concentration falls below optimum
- change detected by alpha cells in Islets of Langerhans in pancreas
- glucagon released
- glycogen converted to glucose
- amino acids converted to glucose
- blood glucose concentration increases due to negative feedback
explain what happens when blood glucose concentration increases above optimum
- change detected by beta cells in Islet of Langerhan in pancreas
- insulin released
- increased respiration in cells
- there is conversion of:
glucose —> glycogen
glucose —-> fats - absorption of glucose into cells
- blood glucose concentration decreases due to negative feedback
explain what happens in type 1 diabetes
pancreas doesn’t produce enough insulin
how is type 1 diabetes controlled
injections of insulin
blood glucose concentration is monitored by biosensors and appropriate amount of insulin is injected
what is type 2 diabetes
less glycoprotein receptors on cells or they lose responsiveness to insulin
how can type 2 diabetes be controlled
regulation of carbohydrate in diet and exercise
Describe how insulin reduces the concentration of glucose in the blood (4 marks)
insulin binds to specific receptors (on membranes);
insulin activates carrier proteins / opens channels / causes more
channels to form;
insulin increases the permeability of liver / muscle cells / tissues to glucose;
insulin action results in glucose conversion to glycogen / glycogenesis;