Pass Med Q's Flashcards

1
Q

what is neuroleptic malignant syndrome

A

rare but dangerous condition seen in patients taking antipsycotic medication

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2
Q

presentation of neuroleptic malignant syndrome

A
pyrexia
muscle rigidity 
HTN, tachycardia, tachypnoea
delirium / agitation / confusion
- symptoms begin within hours to days of starting the medication
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3
Q

what is raised in neuroleptic malignant syndrome

A

CK + leucocytosis

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4
Q

what can occur as a consequence of neuroleptic malignant syndrome

A

AKI secondary to rhabdomyolysis

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5
Q

acute management of cluster headache

A

SC Sumatriptan + oxygen

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6
Q

prophylaxis for cluster headache

A

verapamil

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7
Q

which anti-epileptics can cause Steven Johnston syndrome

A

lamotrigine

carbamazepine

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8
Q

how long do you have to be seizure free to consider stopping anti-epileptic drugs?

A

seizure free for 2 years

- stop drugs over 2-3 month period

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9
Q

what can a tentorial / uncle herniated cause

A

CN III palsy

- fixed dilated pupil, eye is down + out

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10
Q

how long must you stop driving for following a TIA

A

1 month

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11
Q

how long must you stop driving for after 1st unprovoked seizure

A

6 months

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12
Q

bitemporal hemianopia with predominantly lower quadrants affected is caused by what?

A

craniopharyngioma

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13
Q

nerve roots for knee reflex

A

L3 - L4

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14
Q

nerve roots for ankle reflex

A

S1 - S2

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15
Q

nerve roots for biceps reflex

A

C5 - C6

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16
Q

nerve roots for triceps reflex

A

C7 - C8

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17
Q

5 headache red flags that warrant imaging

A
  1. vomiting more than once with no other cause
  2. new motor or sensory defecit
  3. decreased conscious level
  4. headache assoc. with caughing/ sneezing
  5. progressive headache + fever
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18
Q

what is Wernicke’s aphasia

A

receptive aphasia

  • patients can produce fluent speech but sentences don’t make sense
  • comprehension impaired
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19
Q

where is the lesion in Wernickes aphasia

A

superior temporal gyrus

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20
Q

what is Brocas aphasia

A

expressive aphasia

  • speech is non-fluent, laboured, halted
  • comprehension normal
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21
Q

where is the lesion in Brocas aphasia

A

inferior frontal gyrus

22
Q

gold standard test for venous sinus thrombosis

A

MR venogram

23
Q

what condition is suggested by a positive Hoffmans sign

A

degenerative cervical myelopathy

24
Q

most common complication following meningitis

A

sensorineural hearing loss

25
what blood test can be used to differentiate between a seizure and pseudo seizure
prolactin | - prolactin with be raised following a seizure
26
what diagnosis should be suspected in patient with unilateral hearing loss, balance problems and reduced facial sensation
acoustic neuroma (vestibular shwannoma)
27
what reflex can be lost in an acoustic neuroma
corneal reflex
28
Investigation of acoustic neuroma
MRI + audiogram
29
medications post ishcaemic stroke
aspirin 300mg for 2 weeks then clopidogrel 75 mg daily long term
30
first line treatment of trigeminal neuralgia
carbamazepine
31
triad of symptoms wernicke's encephalopathy
confusion, ataxia, opthalmoplegia
32
treatment of wernicke's ecephalopathy
Pabrinex
33
hallucinations, lip smacking, plucking at clothes, deja vu are symptoms of a seizure in what part of the brain?
temporal lobe seizure
34
what are seizures in the parietal lobe associated with?
sensory abnormalities
35
dermatome corresponding to - thumb - middle finger - little finger
thumb = C6 middle finger = C7 little finer = C8
36
what is a Arnold-Chiari malformation
downward displacement / herniation of cerebellar tonsils through foramen magnum
37
what condition can an Arnold-Chiari malformation cause? | how does this present?
syringomyelia | - cape like loss of pain + temperature sensation (spinothalamic tract)
38
tx of tremor in drug induced parkinsons
procyclidine
39
patient with left inferior homonymous hemianopia | where is the lesion?
right parietal lobe
40
isolated rise of protein in CSF on LP indicates what
Guillian Barre
41
what veins are damaged in a sub-dural haemorrhage
bridging veins between cortex and venous sinuses
42
most common psychiatric problem in parkinsons disease
depression
43
which nerve is affected in a RAPD
optic nerve - affected eye will not constrict when light is shone directly in that eye - affected eye will constrict when light is shown in the other eye (consensual response)
44
who typically gets idiopathic intracranial hypertension
young, overweight females
45
features of idiopathic intracranial hypertension
headaches blurred vision papillodema high opening pressure on LP
46
what shoulder movement is most affected in adhesive capsulitis
external rotation
47
what is Kernig's sign
painful knee extension from position of hip + knee flexion | - suggests meningeal irritation e.g. meningitis, SAH
48
occlusion of which artery causes complete aphasia
middle cerebral in the DOMINANT hemisphere | e.g left middle cerebral as most people are right side dominant
49
what condition needs to be excluded in a painful third nerve palsy
posterior communicating artery aneurysm
50
what can trigger cluster headaches
alcohol