part 8 Flashcards
What medications are used to treat PUD?
PPIs (reduce stomach acid
H2R blockers (reduce acid production)
antibiotics (used in common with PPIs to treat H. pylori)
antacids (neutralize stomach acid)
anticholinergics (decrease secretions)
cytoprotective therapy (enhance blood flow)
What are pt’s who are at risk for SRMD stress related mucosal disease will be treated prophylactically with what?
antacids along with an atisecretory agent
Who should not use antacids with magnesium?
pt’t with renal failure sue to high risk of mag toxicity
Who should not use antacids high in sodium? Or use them cautiously.
- older pt’s
- pt’s with cirrhosis
- HTN
- heart failure
- renal disease
How can antacids interact with other drugs?
- can enhance or decrease absorption of other drugs
- potentiate digitalis, stimulants, and oral anticoagulants
Are anticholinergics used for gastric outlet obstruction?
no
- used for short term treatment
- provides protection
- accelerates healing
- give 60 minutes before or after antacids
- sucralfate (reduces bioavailability of some drugs)
- misoprostol
cytoprotective drug therapy
How do tricyclic antidepressants treat PUD?
pain relief
anticholinergic properties
What is the triple drug therapy for H. Pylori
- PPI
- Amoxicillin (antibiotic)
- Clarithromycin (Biaxin-Antibiotic)
- chronic recurrent inflammation of intestinal tract
- periods of remission and exacerbation
- exact cause is unknown
IBD
What are the 2 types of IBD?
Crohns: inflammation of any segment of GI tract (mouth to anus)
Ulcerative: inflammation and ulceration of colon and rectum
What is the etiology of IBD?
- autoimmune: immune response to ones own intestinal tract
- environmental: poor diet, pollution exposure, stress, smoking
- genetic predisposition
